BackgroundAcceptance and Commitment Therapy (ACT) is a type of Cognitive Behavioural Therapy, which has demonstrated positive outcomes in individuals with chronic pain. The purpose of this study was to compare the effect of an 8-week programme combining Exercise with Acceptance and Commitment Therapy (ExACT) with a standalone supervised exercise programme at 1-year follow-up.MethodsOne hundred and seventy-five people with chronic pain were randomly assigned to ExACT or supervised exercise only. The primary outcome was pain interference measured with the Brief Pain Inventory-Interference Scale. Secondary and treatment process outcomes included pain severity, depression, anxiety, pain catastrophizing, pain self-efficacy, fear avoidance, pain acceptance, committed action, healthcare utilization, patient satisfaction, and global impression of change. Estimates of treatment effects at 1-year follow-up were based on intention-to-treat analyses, implemented using a linear mixed-effects model.ResultsEighty-three participants (47.4%) returned the outcome measures at 1-year follow-up. No significant difference was observed between the groups for the primary outcome, pain interference. There was a statistically significant difference between the groups, in favour of ExACT for pain catastrophizing. Within group improvements that were observed within both groups at earlier timepoints were maintained at 1-year follow-up for many of the secondary and treatment process outcomes. ExACT group participants reported higher levels of satisfaction with treatment and global perceived change.ConclusionsThe study results showed no significant difference between the two groups for the primary outcome pain interference at 1-year follow-up. Future research could investigate factors that may predict and optimize outcomes from these types of intervention for people living with chronic pain.SignificanceFew previous randomized controlled trials investigating ACT for chronic pain have included long-term follow-up. This study found that Exercise combined with ACT was not superior to supervised exercise alone for reducing pain interference at 1-year follow-up. Further research is necessary to identify key processes of therapeutic change and to explore how interventions may be modified to enhance clinical outcomes for people with chronic pain.
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Karolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Karolinska Inst, Dept Clin Neurosci, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Rickardsson, Jenny
Gentili, Charlotte
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Karolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Karolinska Inst, Dept Clin Neurosci, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Gentili, Charlotte
Holmstrom, Linda
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Karolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Holmstrom, Linda
Zetterqvist, Vendela
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Karolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden
Uppsala Univ, Dept Neurosci, Uppsala, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Zetterqvist, Vendela
Andersson, Erik
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Karolinska Inst, Dept Clin Neurosci, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Andersson, Erik
Persson, Jan
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Karolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Persson, Jan
Lekander, Mats
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Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden
Stockholm Univ, Stress Res Inst, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Lekander, Mats
Ljotsson, Brjann
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Karolinska Inst, Dept Clin Neurosci, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
Ljotsson, Brjann
Wicksell, Rikard K.
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Karolinska Inst, Dept Clin Neurosci, Stockholm, SwedenKarolinska Univ Hosp, Funct Unit Behav Med, S-17176 Stockholm, Sweden
机构:
Univ Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, SpainUniv Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, Spain
Fernández-de-las-Peñas, C
Alonso-Blanco, C
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Univ Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, SpainUniv Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, Spain
Alonso-Blanco, C
Alguacil-Diego, IM
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Univ Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, SpainUniv Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, Spain
Alguacil-Diego, IM
Miangolarra-Page, JC
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Univ Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, SpainUniv Rey Juan Carlos, Fac Ciencias Salud, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, Spain
机构:
Orebro Cty Council, Rehabil Res Ctr, Orebro, Sweden
Univ Orebro, Sch Law Psychol & Social Work, SE-70182 Orebro, Sweden
Univ Orebro, Sch Hlth & Med Sci, SE-70182 Orebro, SwedenOrebro Cty Council, Rehabil Res Ctr, Orebro, Sweden
Lundqvist, Lars-Olov
Zetterlund, Christina
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Orebro Cty Council, Rehabil Res Ctr, Orebro, Sweden
Univ Orebro, Sch Hlth & Med Sci, SE-70182 Orebro, Sweden
Orebro Cty Council, Low Vis Ctr, Orebro, SwedenOrebro Cty Council, Rehabil Res Ctr, Orebro, Sweden