Central Nervous System Histoplasmosis: An Updated Insight

被引：1
|
作者：
Ramirez, Jose Antonio [1 ]
Reyes-Montes, Maria del Rocio [1 ]
Rodriguez-Arellanes, Gabriela [1 ]
Perez-Torres, Armando [2 ]
Taylor, Maria Lucia [1 ]
机构：
[1] Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol Parasitol, Unidad Micol, Mexico City 04510, Mexico
[2] Univ Nacl Autonoma Mexico, Fac Med, Dept Biol Celular & Tisular, Mexico City 04510, Mexico
来源：
PATHOGENS | 2023年 / 12卷 / 05期
关键词：
H; capsulatum; dissemination; CNS infection; histoplasmomas; host's CNS injuries; POLYMERASE-CHAIN-REACTION; MOLECULAR-DETECTION; CAPSULATUM DNA; NESTED PCR; DIAGNOSIS; IDENTIFICATION; REGION; MENINGITIS; INFECTIONS; MANAGEMENT;
D O I：
10.3390/pathogens12050681
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Histoplasmosis is one of the systemic mycoses that can involve the Central Nervous System (CNS), and it is caused by the dimorphic ascomycete species of the Histoplasma capsulatum complex. Once in the CNS, this pathogen causes life-threatening injuries that are associated with clinical manifestations of meningitis, focal lesions (abscesses, histoplasmomas), and spinal cord injuries. The present review provides updated data and highlights a particular vision regarding this mycosis and its causative agent, as well as its epidemiology, clinical forms, pathogenesis, diagnosis, and therapy, focusing on the CNS.
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页数：10
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