Low-Cost Portable Medical Device for the Detection and Quantification of Exosomes

被引：0

作者：

Barrettino, Diego ^{[1
]}

Zumbuhl, Christoph ^{[1
]}

Kummer, Raphael ^{[1
]}

Thalmann, Markus ^{[1
]}

Balbi, Carolina ^{[2
]}

Vassalli, Giuseppe ^{[2
]}

Dos Santos, Rosane Moura ^{[3
]}

Sallese, Jean-Michel ^{[3
]}

机构：

[1] Lucerne Univ Appl Sci & Arts HSLU, Inst Elect Engn, CH-6048 Horw, Switzerland

[2] Ist Cardioctr Ticino, Via Tesserete 48, CH-6900 Lugano, Switzerland

[3] Swiss Fed Inst Technol Lausanne EPFL, EPFL SCI STI EDLAB, Stn 11, CH-1015 Lausanne, Switzerland

来源：

2023 IEEE SENSORS | 2023年

关键词：

Biomedical Diagnostics; Exosomes; Biosensors; Microfluidics; Readout and Control Electronics; ELECTRICAL DETECTION;

D O I：

10.1109/SENSORS56945.2023.10325271

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The design, fabrication and testing of a low-cost portable medical device for the detection and quantification of exosomes is presented in this paper. The portable medical device comprises a sensor array that can detect the presence of exosomes and quantify its concentration, a micro fluidic device that handles the human serum containing the exosomes, and all the necessary readout and control electronics. Measurement results performed with exosomes showed that the portable medical device can detect exosomes with a concentration of 2.5x10(8)/mu L thus paving the way to a wide range of diagnostic applications.

引用

页数：4

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