Extrinsic lipoid pneumonia due to chronic polyethylene glycol consumption: A case report

被引:1
|
作者
Murphy, Robert J. [1 ]
Tessier, Steven [1 ]
Longo, Santo [2 ]
Alia, Christopher S. [3 ]
Ido, Firas [3 ]
机构
[1] Temple Univ, Lewis Katz Sch Med, 3500 N Broad St,Suite 124, Philadelphia, PA 19140 USA
[2] St Lukes Univ Hlth Network, Dept Pathol, 801 Ostrum St, Bethlehem, PA 18015 USA
[3] St Lukes Univ Hlth Network, Dept Pulmonol & Crit Care, 801 Ostrum St, Bethlehem, PA 18015 USA
关键词
Lipoid pneumonia; Polyethylene glycol; Hounsfeld units; Oil-Red-O; Foamy macrophages;
D O I
10.1016/j.resinv.2023.08.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Extrinsic lipoid pneumonia (ELP) results from the aspiration of lipid-containing substances. Tissue or cell histopathology after Oil-Red-O staining can confirm the diagnosis, which requires proper tissue handling and preparation during bronchoscopy. Here, we report a case of ELP in a quadriplegic patient with a long history of dysphagia and polyethylene glycol consumption. Computed tomography (CT) of the chest revealed multiple, progres-sively enlarging, fat-attenuated, nodular pulmonary lesions. Bronchoscopy with bron-choalveolar lavage (BAL) and a transbronchial forceps biopsy confirmed the diagnosis of lipoid pneumonia. We discuss the clinical, radiological, and pathological features of ELP and highlight the preparatory steps required for obtaining a successful diagnosis. (c) 2023 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.
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页码:768 / 772
页数:5
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