The impact of thromboelastography on patients with penetrating abdominal trauma requiring intensive care

被引:0
|
作者
Hannington, M. [1 ]
Nel, D. [1 ]
Miller, M. [1 ,2 ]
Nicol, A. [1 ]
Navsaria, P. [1 ,3 ]
机构
[1] Univ Cape Town, Groote Schuur Hosp, Dept Gen Surg, Cape Town, South Africa
[2] Univ Cape Town, Groote Schuur Hosp, Dept Crit Care, Cape Town, South Africa
[3] Univ Cape Town, Groote Schuur Hosp, Trauma Surg, Cape Town, South Africa
关键词
thromboelastography; penetrating abdominal trauma; critical care; FIBRINOLYSIS SHUTDOWN; DAMAGE CONTROL; COAGULOPATHY; MORTALITY; THROMBELASTOGRAPHY; HYPOCOAGULABILITY; TRANSFUSION; HYPOTHERMIA; ACIDOSIS; INJURY;
D O I
10.36303/SAJS.3950
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Trauma-induced coagulopathy (TIC) is a complex multifaceted process which contributes to higher mortality rates in severely injured trauma patients. Thromboelastography (TEG) is effective in detecting TIC which assists in instituting goal-directed therapy as part of damage control resuscitation.Methods: This retrospective study included all adult patients over a 36-month period with penetrating abdominal trauma who required a laparotomy, blood products and admission for critical care. Analysis included demographics, admission data, 24-hour interventions, TEG parameters and 30-day outcomes.Results: Eighty-four patients with a median age of 28 years were included. The majority (93%; 78/84) suffered from a gunshot injury, with 75% (63/84) receiving a damage control laparotomy. Forty-eight patients (57%) had a TEG. Injury severity score and total fluid and blood product administered in the first 24 hours were all significantly higher in patients who had a TEG (p < 0.05). TEG profiles were: 42% (20/48) normal, 42% (20/48) hypocoagulable, 12% (6/48) hypercoagulable and 4% (2/48) mixed parameters. Fibrinolysis profiles were: 48% (23/48) normal, 44% (21/48) fibrinolysis shutdown and 8% (4/48) hyperfibrinolysis. Mortality rate was 5% (4/84) at 24 hours and 26% (22/84) at 30 days, with no difference between the two groups. High-grade complication rates, days on a ventilator and intensive care unit length of stay were all significantly higher in patients who did not have a TEG.Conclusion: TIC is common in severely injured penetrating trauma patients. The usage of a thromboelastogram did not impact on 24-hour or 30-day mortality but did result in a decreased intensive care stay and a decreased high-grade
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页码:133 / 138
页数:6
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