Palladium-catalyzed Cross-coupling of 2-Benzo[b]thiophene or 2-Benzo[b]furan Aluminum with Heteroaryl or Alkynyl Bromides for the Synthesis of 2-Hetroaryl or Alkynyl Benzo[b]thiophene or Benzo[b]furan Derivatives

被引：3

作者：

Liang, Meng ^{[1
,2
]}

Pu, Jiaxia ^{[1
,2
]}

Jia, Xiaoying ^{[1
,2
]}

Han, Lirong ^{[1
,2
]}

Li, Qinghan ^{[1
,2
,3
]}

机构：

[1] Southwest Minzu Univ, Coll Chem & Environm, Chengdu 610041, Peoples R China

[2] Southwest Minzu Univ, Coll Chem & Environm, Key Lab Gen Chem Natl Ethn Affairs Commiss, Chengdu 610041, Peoples R China

[3] Southwest Minzu Univ, Coll Chem & Environm, POB 610041, Chengdu, Peoples R China

来源：

LETTERS IN ORGANIC CHEMISTRY | 2024年 / 21卷 / 02期

关键词：

Palladium; 2-benzo[b]thiophene; 2-benzo[b]furan; alkynyl bromide; heteroaryl aluminum; cross-coupling reaction; ONE-POT SYNTHESIS; ELECTROPHILIC CYCLIZATION; RESEARCH PROGRESS; TERMINAL ALKYNES; FUNCTIONALIZATION; NANOPARTICLES; HYDROALKOXYLATION; BENZOTHIOPHENES; BENZOFURANS; ANNULATION;

D O I：

10.2174/1570178620666230821142342

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An alternative method for the synthesis of 2-heteroaryl or alkynyl benzo[b]thiophene or furan derivatives via direct palladium-catalyzed cross-coupling of 2-benzo[b]thiophene or furan aluminum with heteroaryl or alkynyl bromides, respectively, has been successfully developed. This case is remarkable as the same catalytic system could simultaneously produce either 2-substituted benzo[b]thiophene or furan derivatives.

引用

页码：116 / 123

页数：8

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