Metformin: A Potential Treatment for Acne, Hidradenitis Suppurativa and Rosacea

被引：3
|
作者：
Cho, Minah [1 ]
Woo, Yu Ri [1 ]
Cho, Sang Hyun [1 ]
Lee, Jeong Deuk [1 ]
Sung, Hei [1 ]
机构：
[1] Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Dept Dermatol, Seoul, South Korea
来源：
ACTA DERMATO-VENEREOLOGICA | 2023年 / 103卷
关键词：
acne vulgaris; hidradenitis suppurativa; metformin; rosacea; GROWTH-FACTOR-I; NF-KAPPA-B; CLINICAL-APPLICATIONS; TUMOR ANGIOGENESIS; FIBROSIS; THERAPY; SKIN; ANDROGEN; PATHWAY; INSULIN;
D O I：
10.2340/actadv.v103.18392
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Metformin is a widely used drug for treatment of diabetes mellitus, due to its safety and efficacy. In addition to its role as an antidiabetic drug, numerous beneficial effects of metformin have enabled its use in various diseases. Considering the anti-androgenic, anti-angiogenic, anti-fibrotic and antioxidant properties of metformin, it may have the potential to improve chronic inflammatory skin diseases. However, further evidence is needed to confirm the efficacy of metformin in dermatological conditions, This review focuses on exploring the therapeutic targets of metformin in acne vulgaris, hidradenitis suppurativa and rosacea, by studying their pathogeneses.
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页数：10
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