共 3 条
- [1] The mechanistic basis of both deep and durable antitumor activity by combinatorial inhibition of MAT2A and PRMT5 in MTAP-deleted tumorsEUROPEAN JOURNAL OF CANCER, 2024, 211 : S84 - S84Garbett, D.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USARao, A. A.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Computat Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAFischer, M. M.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Pharmacol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USABelmontes, B.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Oncol Res, Thousand Oaks, CA USA Ideaya Biosci, Biol, South San Francisco, CA USASlemmons, K.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Oncol Res, Thousand Oaks, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAAppel, M. J.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Lead Discovery, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAFang, Z.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Lead Discovery, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAChoy, R.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Lead Discovery, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USATyler, S. R.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Computat Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAVivian, J.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Computat Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAFreyman, Y.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Pharmacol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAMagallanes, K.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USALanham, P.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Biol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USARathore, A.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, DMPK & Clin Pharmacol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USALi, A.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, DMPK & Clin Pharmacol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAAubi, O.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Lead Discovery, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAHughes, P. E.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Oncol Res, Thousand Oaks, CA USA Ideaya Biosci, Biol, South San Francisco, CA USATeriete, P.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Lead Discovery, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USAWhite, M. A.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USANeilan, C. L.论文数: 0 引用数: 0 h-index: 0机构: Ideaya Biosci, Pharmacol, South San Francisco, CA USA Ideaya Biosci, Biol, South San Francisco, CA USA
- [2] Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibitionJOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (01)Bedard, Gabriel T.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAGilaj, Nord论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA Lehman Coll, Dept Chem, Bronx, NY USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAPeregrina, Karina论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Oncol, Bronx, NY USA Albert Einstein Coll Med, Dept Med, Bronx, NY USA Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USABrew, Isabella论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USATosti, Elena论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Genet, Bronx, NY USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAShaffer, Karl论文数: 0 引用数: 0 h-index: 0机构: Victoria Univ Wellington, Ferrier Res Inst, Lower Hutt, New Zealand Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USATyler, Peter C.论文数: 0 引用数: 0 h-index: 0机构: Victoria Univ Wellington, Ferrier Res Inst, Lower Hutt, New Zealand Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAEdelmann, Winfried论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Genet, Bronx, NY USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAAugenlicht, Leonard H.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Oncol, Bronx, NY USA Albert Einstein Coll Med, Dept Med, Bronx, NY USA Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USASchramm, Vern L.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA
- [3] A phase I study of synthetic lethal, IDE397 (MAT2A inhibitor) as a monotherapy and in combination with chemotherapy in advanced solid tumors harboring MTAP deletionANNALS OF ONCOLOGY, 2022, 33 (07) : S766 - S767Johnson, M. L.论文数: 0 引用数: 0 h-index: 0机构: Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USARodon, J.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Drug Dev Dept, Houston, TX USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAAljumaily, R.论文数: 0 引用数: 0 h-index: 0机构: Univ Oklahoma, Stephenson Canc Ctr, Hematol, Oncol, Oklahoma City, OK USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAVillalona-Calero, M.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, Early Phase Therapeut Program, Duarte, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USABorazanci, E.论文数: 0 引用数: 0 h-index: 0机构: HonorHlth Res Inst, Med Oncol, Scottsdale, AZ USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAPishvaian, M.论文数: 0 引用数: 0 h-index: 0机构: Johns Hopkins Univ, Oncol Dept, Baltimore, MD USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USATurk, A.论文数: 0 引用数: 0 h-index: 0机构: Indiana Univ, Simon Canc Ctr, Med Oncol Dept, Indianapolis, IN USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USACarvajal, R. D.论文数: 0 引用数: 0 h-index: 0机构: Columbia Univ, Med Ctr, Coll Phys & Surg, New York Presbyterian Hosp,Div Hematol Oncol, New York, NY USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAMantia, C.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Genitourinary Oncol Dept, Boston, MA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAGiaccone, G.论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Med, Oncol, New York, NY USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAMounir, Z.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, Translat Sci Dept, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAPatel, A.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, Clin Dev, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAMaurer, M.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, Clin Dev, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USANeilan, C.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, Preclin Sci, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USARajendran, D.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAGanesan, U.论文数: 0 引用数: 0 h-index: 0机构: IDEAYA Biosci, San Francisco, CA USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USAHinkle, J.论文数: 0 引用数: 0 h-index: 0机构: EarlyPhase Sci Inc, Biostat, Magnolia, TX USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USATolcher, A. W.论文数: 0 引用数: 0 h-index: 0机构: NEXT OncologyTM, San Antonio, TX USA Sarah Cannon Res Inst, Canc Ctr, Lung Canc Res, Nashville, TN USA