Idiopathic Oxalate Nephropathy Leading to End-Stage Kidney Disease: A Case Report

被引:0
|
作者
Saleem, Maryam [1 ,2 ,3 ]
Shahjahan, Khadija [4 ]
Iftikhar, Hassaan [1 ,5 ,6 ]
机构
[1] Ohio Valley Nephrol Associates, Nephrol, Owensboro, KY 42303 USA
[2] Washington Univ, Sch Med, Nephrol, St Louis, MO 63130 USA
[3] Waterbury Hosp & Hlth Ctr, Internal Med, Waterbury, CT 06708 USA
[4] Faisalabad Med Univ, Internal Med, Faisalabad, Pakistan
[5] Washington Univ, Sch Med, Nephrol, St Louis, MO USA
[6] St Francis Med Ctr, Internal Med, Trenton, NJ USA
关键词
end stage kidney disease (eskd); idiopathic hyperoxaluria; primary hyperoxaluria; oxalate nephropathy; aki; MANAGEMENT; MECHANISMS;
D O I
10.7759/cureus.42402
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Oxalate nephropathy represents a frequently overlooked etiology of renal failure, characterized by the deposition of calcium oxalate crystals within the renal parenchyma. This progressive form of kidney disease is marked by a significant increase in serum creatinine (Cr) level accompanied by evidence of oxalate crystal deposition on renal biopsy causing tubular obstruction and tubular injury leading to fibrosis. In all instances of oxalate nephropathy, examination of stones consistently exhibits multiple birefringent calcium oxalate crystals under polarized light. This case report details the clinical course of a patient who initially presented with progressively worsening renal function and ultimately developed end-stage kidney disease (ESKD) as a consequence of idiopathic hyperoxaluria.
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页数:4
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