Extensive Skeletal Muscle Metastases in Malignant Pleural Mesothelioma Detected by FDG PET/CT

被引:0
|
作者
Yilmaz, Mustafa [1 ,3 ]
Kandemir, Ozan [1 ]
Tutar, Ediz [2 ]
机构
[1] Mugla Sitki Kocman Univ, Sch Med, Dept Nucl Med, Mugla, Turkiye
[2] Ozel Biyotip Pathol Lab, Bursa, Turkiye
[3] MSKU Sch Med, Dept Nucl Med, TR-48040 Mugla, Turkiye
关键词
malignant pleural mesothelioma; skeletal muscle metastasis; FDG PET/CT; contrast-enhanced CT; MANIFESTATION; CT;
D O I
10.1055/s-0043-1774730
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Malignant pleural mesothelioma (MPM) is a rare but aggressive tumor originating from pleural mesothelial cells. Distant skeletal muscle metastasis is rare in MPM. A 54-year-old woman was diagnosed with epithelioid MPM and treated with surgery, chemotherapy, and radiotherapy 2 years ago. During follow-up, diffuse irregular pleural thickening with focal chest wall invasion in the right hemithorax and two small pleural thickenings in the left hemithorax were seen on control diagnostic contrast-enhanced computed tomography (CECT). Fluorine-18 fluorodeoxyglucose positron emission tomography/CT (FDG PET/CT) imaging was performed as part of restaging. PET showed diffusely increased FDG uptake in the recurrent right pleural tumor, and two hypermetabolic small metastatic foci in the contralateral pleura. In addition, multiple hypermetabolic areas of various sizes in various skeletal muscle localizations, suggestive of extensive muscle metastases were noted. Histopathologic study confirmed metastatic epithelioid MPM. FDG PET/CT revealed multiple muscle metastases which were not observed on earlier CECT and contributed to the visualization of more extensive metastatic involvements in the presented case with MPM. FDG PET/CT can detect rarely seen skeletal muscle metastases that are not visualized on diagnostic CT, and provides more accurate restaging of MPM.
引用
收藏
页码:293 / 296
页数:4
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