Structural elucidation of lactone derivatives from Dendrobium pendulum

被引：0

作者：

Zhang, Mao-Sheng ^{[1
,2
]}

Jiang, Yu ^{[3
]}

Cheng, Lei ^{[4
]}

Yang, Jian-Wen ^{[1
,2
]}

Dong, Min-Jian ^{[1
,2
]}

Sun, Cheng-Xin ^{[1
,2
]}

Xiao, Shi-Ji ^{[1
,2
]}

机构：

[1] Zunyi Med Univ, Key Lab Basic Pharmacol Guizhou Prov, Zunyi 563000, Guizhou, Peoples R China

[2] Zunyi Med Univ, Sch Pharm, Zunyi 563000, Guizhou, Peoples R China

[3] Sichuan Nursing Vocat Coll, Dept Nursing, Deyang, Peoples R China

[4] First Peoples Hosp Bijie City, Dept Pharm, Bijie, Peoples R China

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2023年 / 61卷 / 08期

关键词：

Dendrobium pendulum; Orchidaceae; structural elucidation; alpha-furanone; alpha-pyrones;

D O I：

10.1002/mrc.5370

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Six lactone derivatives, including four a-pyrones derivatives (1-4), two a-furanone derivatives (5 and 6), were isolated from the Dendrobium pendulum. Structural elucidation of these undescribed lactone derivatives were accomplished on the basis of detailed nuclear magnetic resonance analysis, and the absolute configurations of compounds 1-4 were confirmed by electronic circular dichroism (ECD) techniques. The cytotoxic effects of isolated compounds on human breast cancer cell MDA-MB-231 were evaluated by the MTT assay.

引用

页码：481 / 486

页数：6

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