Ixazomib-Thalidomide-Dexamethasone Induction Followed by Ixazomib or Placebo Maintenance in Nontransplant Eligible Newly Diagnosed Multiple Myeloma Patients: Long-term Results of HOVON-126/NMSG 21.13

被引：1

作者：

Groen, Kazimierz ^{[1
,2
]}

Schjesvold, Fredrik H. ^{[3
,4
]}

van der Holt, Bronno ^{[5
]}

Levin, Mark-David ^{[6
]}

Seefat, Maarten R. ^{[1
,2
]}

Hansson, Markus ^{[7
]}

Leys, Maria B. L. ^{[8
]}

Regelink, Josien C. ^{[9
]}

Waage, Anders ^{[10
]}

Szatkowski, Damian ^{[11
]}

Axelsson, Per ^{[12
]}

Hieu Do, Trung ^{[13
]}

Svirskaite, Asta ^{[14
]}

van der Spek, Ellen ^{[15
]}

Haukas, Einar ^{[16
]}

Knut-Bojanowska, Dorota ^{[17
]}

Ypma, Paula F. ^{[18
]}

Blimark, Cecilie H. ^{[19
]}

Mellqvist, Ulf-Henrik ^{[20
]}

van de Donk, Niels W. C. J. ^{[1
,2
]}

Sonneveld, Pieter ^{[21
]}

Klostergaard, Anja ^{[22
]}

Vangsted, Annette J. ^{[23
]}

Abildgaard, Niels ^{[24
,25
,26
]}

Zweegman, Sonja ^{[1
,2
]}

机构：

[1] Vrije Univ, Amsterdam UMC, Dept Hematol, Amsterdam, Netherlands

[2] Canc Ctr Amsterdam, Treatment & Qual Life, Amsterdam, Netherlands

[3] Oslo Univ Hosp, OSlo Myeloma Ctr, Dept Hematol, Oslo, Norway

[4] Univ Oslo, KG Jebsen Ctr Cell Malignancies B, Oslo, Norway

[5] Erasmus MC Canc Inst, HOVON Data Ctr, Dept Hematol, Rotterdam, Netherlands

[6] Albert Schweitzer Hosp, Dept Internal Med, Dordrecht, Netherlands

[7] Skane Univ Hosp Lund, Dept Hematol, Skane, Sweden

[8] Maasstad Hosp, Dept Internal Med, Rotterdam, Netherlands

[9] Meander Med Ctr, Dept Internal Med, Amersfoort, Netherlands

[10] Norwegian Univ Sci & Technol NTNU, Inst Clin & Mol Med, Trondheim, Norway

[11] Forde Cent Hosp, Dept Oncol & Hematol, Forde, Norway

[12] Helsinborg Hosp, Dept Internal Med, Helsingborg, Sweden

[13] Roskilde Sjaelland Univ, Haematol Dept H 60, Roskilde, Denmark

[14] Aalborg Univ Hosp, Dept Hematol, Aalborg, Denmark

[15] Rijnstate Hosp, Dept Internal Med, Arnhem, Netherlands

[16] Stavanger Univ Hosp, Dept Blood & Canc Dis, Stavanger, Norway

[17] Uddevalla Cent Hosp, Inst Heamatol, Uddevalla, Sweden

[18] Haga Hosp, Dept Hematol, The Hague, Netherlands

[19] Sahlgrens Univ Hosp, Hematol Dept, Gothenburg, Sweden

[20] Sodra Alvsborgs Sjukhus, Dept Internal Med, Boras, Sweden

[21] Erasmus MC Canc Inst, Dept Hematol, Rotterdam, Netherlands

[22] Aarhus Univ Hosp, Dept Hematol, Aarhus, Denmark

[23] Rigshosp, Dept Hematol, Copenhagen, Denmark

[24] Odense Univ Hosp, Dept Hematol, Hematol Res Unit, Odense, Denmark

[25] Odense Univ Hosp, Acad Geriatr Res, Odense, Denmark

[26] Univ Southern Denmark, Odense, Denmark

来源：

HEMASPHERE | 2023年 / 7卷 / 09期

关键词：

STEM-CELL TRANSPLANTATION; THERAPY; BORTEZOMIB;

D O I：

10.1097/HS9.0000000000000940

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4

共 50 条

[1] Ixazomib-thalidomide-low dose dexamethasone induction followed by maintenance therapy with ixazomib or placebo in newly diagnosed multiple myeloma patients not eligible for autologous stem cell transplantation; results from the randomized phase II HOVON-126/NMSG 21.13 trial
Zweegman, Sonja
Stege, Claudia A. M.
Haukas, Einar
Schjesvold, Fredrik H.
Levin, Mark-David
Waage, Anders
Leys, Rineke B. L.
Klein, Saskia K.
Szatkowski, Damian
Axelsson, Per
Trung Hieu Do
Knut-Bojanowska, Dorota
van der Spek, Ellen
Svirskaite, Asta
Klostergaard, Anja
Salomo, Morten
Blimark, Celine
Ypma, Paula F.
Mellqvist, Ulf-Hendrik
Poddighe, Pino J.
Stevens-Kroef, Marian
van de Donk, Niels W. C. J.
Sonneveld, Pieter
Hansson, Markus
van der Holt, Bronno
Abildgaard, Niels
[J]. HAEMATOLOGICA, 2020, 105 (12) : 2879 - 2882
[2] Ixazomib-Thalidomide-Low Dose Dexamethasone (ITd) Induction Followed By Maintenance Therapy with Ixazomib or Placebo in Newly Diagnosed Multiple Myeloma Patients Not Eligible for Autologous Stem Cell Transplantation; Initial Results from the Randomized Phase II HOVON-126/Nmsg 21.13 Trial
Zweegman, Sonja
van der Holt, Bronno
Schjesvold, Fredrik H.
Levin, Mark-David
Stege, Claudia A. M.
Waage, Anders
Leijs, Maria Berhardina
Klein, Saskia
Szatkowski, Damian L.
Broyl, A.
Axelsson, Per
Trung Hieu Do
Knut-Bojanovska, Dorota
van der Spek, Ellen
Svirskaite, Asta
Cunha, Sonia
Hansson, Markus
Sonneveld, Pieter
Haukaas, Einar
Abildgaard, Niels
[J]. BLOOD, 2017, 130
[3] Ixazomib-Thalidomide-Low Dose Dexamethasone (ITd) Induction Followed By Maintenance Therapy with Ixazomib or Placebo in Newly Diagnosed Multiple Myeloma Patients Not Eligible for Autologous Stem Cell Transplantation; Results from the Randomized Phase II HOVON-126/Nmsg 21#13 Trial
Zweegman, Sonja
Schjesvold, Fredrik H.
van der Holt, Bronno
Levin, Mark-David
Stege, Claudia A. M.
Waage, Anders
Leijs, Maria B. L.
Klein, Saskia K.
Szatkowski, Damian L.
Axelsson, Per
Trung Hieu Do
Knut-Bojanovska, Dorota
van der Spek, Ellen
Svirskaite, Asta
Poddighe, Pino
Stevens-Kroef, Marian
Hansson, Markus
van de Donk, Niels W. C. J.
Haukas, Einar
Sonneveld, Pieter
Abildgaard, Niels
[J]. BLOOD, 2018, 132
[4] Ixazomib-Thalidomide-Dexamethasone for induction therapy followed by Ixazomib maintenance treatment in patients with relapsed/refractory multiple myeloma
Ludwig, Heinz
Poenisch, Wolfram
Knop, Stefan
Egle, Alexander
Schreder, Martin
Lechner, Daniel
Hajek, Roman
Gunsilius, Eberhard
Krenosz, Karl Jochen
Petzer, Andreas
Weisel, Katja
Niederwieser, Dietger
Einsele, Hermann
Willenbacher, Wolfgang
Melchardt, Thomas
Greil, Richard
Zojer, Niklas
[J]. BRITISH JOURNAL OF CANCER, 2019, 121 (09) : 751 - 757
[5] Ixazomib–Thalidomide–Dexamethasone for induction therapy followed by Ixazomib maintenance treatment in patients with relapsed/refractory multiple myeloma
Heinz Ludwig
Wolfram Poenisch
Stefan Knop
Alexander Egle
Martin Schreder
Daniel Lechner
Roman Hajek
Eberhard Gunsilius
Karl Jochen Krenosz
Andreas Petzer
Katja Weisel
Dietger Niederwieser
Hermann Einsele
Wolfgang Willenbacher
Thomas Melchardt
Richard Greil
Niklas Zojer
[J]. British Journal of Cancer, 2019, 121 : 751 - 757
[6] Ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance
Shaji K. Kumar
Jesus G. Berdeja
Ruben Niesvizky
Sagar Lonial
Jacob P. Laubach
Mehdi Hamadani
A. Keith Stewart
Parameswaran Hari
Vivek Roy
Robert Vescio
Jonathan L. Kaufman
Deborah Berg
Eileen Liao
S. Vincent Rajkumar
Paul G. Richardson
[J]. Leukemia, 2019, 33 : 1736 - 1746
[7] Ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance
Kumar, Shaji K.
Berdeja, Jesus G.
Niesvizky, Ruben
Lonial, Sagar
Laubach, Jacob P.
Hamadani, Mehdi
Stewart, A. Keith
Hari, Parameswaran
Roy, Vivek
Vescio, Robert
Kaufman, Jonathan L.
Berg, Deborah
Liao, Eileen
Rajkumar, S. Vincent
Richardson, Paul G.
[J]. LEUKEMIA, 2019, 33 (07) : 1736 - 1746
[8] Health-Related Quality of Life in Patients with Relapsed/Refractory Multiple Myeloma during Treatment with Ixazomib-Thalidomide-Dexamethasone Followed By Ixazomib Maintenance
Ludwig, Heinz
Ponisch, Wolfram
Egle, Alexander
Knop, Stefan
Schreder, Martin
Lechner, Daniel
Hajek, Roman
Gunsilius, Eberhard
Fridrik, Michael A.
Petzer, Andreas
Weisel, Katja C.
Niederwieser, Dietger
Hinke, Axel
Greil, Richard
Zojer, Niklas
[J]. BLOOD, 2017, 130
[9] Quality of life in patients with relapsed/refractory multiple myeloma during ixazomib-thalidomide-dexamethasone induction and ixazomib maintenance therapy and comparison to the general population
Ludwig, Heinz
Poenisch, Wolfram
Knop, Stefan
Egle, Alexander
Hinke, Axel
Schreder, Martin
Lechner, Daniel
Hajek, Roman
Gunsilius, Eberhard
Petzer, Andreas
Weisel, Katja
Niederwieser, Dietger
Einsele, Hermann
Willenbacher, Wolfgang
Rumpold, Holger
Pour, Ludek
Jelinek, Tomas
Krenosz, Karl Jochen
Meckl, Angela
Nolte, Sandra
Melchardt, Thomas
Greil, Richard
Zojer, Niklas
[J]. LEUKEMIA & LYMPHOMA, 2020, 61 (02) : 377 - 386
[10] Efficacy and Safety of Ixazomib-Dexamethasone, Ixazomib-Cyclophosphamide-Dexamethasone, Ixazomib-Thalidomide-Dexamethasone and Ixazomib-Bendamustine-Dexamethasone for Elderly Newly Diagnosed Multiple Myeloma (NDMM) Patients: Analysis of the Phase II Randomized Unito-EMN10 Study
Larocca, Alessandra
Corradini, Paolo
Mina, Roberto
Cascavilla, Nicola
Liberati, Anna Marina
Pescosta, Norbert
Petrucci, Maria Teresa
Ciccone, Giovannino
Capra, Andrea
Patriarca, Francesca
Scalabrini, Delia Rota
Innao, Vanessa
Poggiu, Marco
Cea, Michele
Zambello, Renato
Baraldi, Anna
Belotti, Angelo
Cellini, Claudia
Galli, Monica
Grasso, Mariella
Aquino, Sara
Casaluci, Gloria Margiotta
De Sabbata, Giovanni
Ballanti, Stelvio
Offidani, Massimo
Mancuso, Katia
Boccadoro, Mario
Bringhen, Sara
[J]. BLOOD, 2019, 134

← 1 2 3 4 5 →