Heat Capacities of N-Acetyl Amides of Glycine, L-Alanine, L-Valine, L-Isoleucine, and L-Leucine

被引:1
|
作者
Stejfa, Vojtech [1 ]
Pokorny, Vaclav [1 ,2 ]
Lieberzeitova, Eliska [1 ]
Havlin, Jakub [3 ]
Fulem, Michal [1 ]
Ruzicka, Kvetoslav [1 ]
机构
[1] Univ Chem & Technol, Dept Phys Chem, Tech 5, CZ-16628 Prague, Czech Republic
[2] Czech Acad Sci, Inst Macromol Chem, Heyrovskeho Nam 2, CZ-16206 Prague, Czech Republic
[3] Univ Chem & Technol, Cent Labs, Tech 5, CZ-16628 Prague, Czech Republic
来源
MOLECULES | 2023年 / 28卷 / 14期
关键词
N-acetyl glycine amide; N-acetyl-L-alanine amide; N-acetyl-L-valine amide; N-acetyl-L-isoleucine amide; N-acetyl-L-leucine amide; crystalline phase; heat capacity; THERMODYNAMICS; ENTHALPIES; ENTROPIES; FUSION;
D O I
10.3390/molecules28145440
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
As a follow-up to our effort to establish reliable thermodynamic data for amino acids, the heat capacity and phase behavior are reported for N-acetyl glycine amide (CAS RN: 2620-63-5), N-acetyl-L-alanine amide (CAS RN: 15962-47-7), N-acetyl-L-valine amide (CAS RN: 37933-88-3), N-acetyl-L-isoleucine amide (CAS RN: 56711-06-9), and N-acetyl-L-leucine amide (CAS RN: 28529-34-2). Prior to heat capacity measurement, thermogravimetric analysis and X-ray powder diffraction were performed to determine decomposition temperatures and initial crystal structures, respectively. The crystal heat capacities of the five N-acetyl amino acid amides were measured by Tian-Calvet calorimetry in the temperature interval (266-350 K), by power compensation DSC in the temperature interval (216-471 K), and by relaxation (heat-pulse) calorimetry in the temperature interval (2-268 K). As a result, reference heat capacities and thermodynamic functions for the crystalline phase from 0 K up to 470 K were developed.
引用
收藏
页数:14
相关论文
共 50 条