A new way to create ether lipids

被引：1

作者：

Lee, Ji-Yoon ^{[1
]}

Kim, Jong Woo ^{[1
,2
]}

Lee, Eun-Woo ^{[1
,2
,3
]}

机构：

[1] Korea Res Inst Biosci & Biotechnol KRIBB, Metab Regulat Res Ctr, Daejeon, South Korea

[2] Univ Sci & Technol UST, Dept Funct Genom, Daejeon, South Korea

[3] Sungkyunkwan Univ, Sch Pharm, Suwon, South Korea

来源：

NATURE CHEMICAL BIOLOGY | 2023年 / 19卷 / 03期

关键词：

FERROPTOSIS;

D O I：

10.1038/s41589-023-01255-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A crucial step in the cell-death process of ferroptosis is the incorporation of free polyunsaturated fatty acids (PUFAs) into membrane phospholipids. An enzyme has now been identified that contributes to ferroptosis by directly transferring PUFAs from phospholipids to ether lysophospholipids to form ether phospholipids.

引用

页码：259 / 260

页数：2

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