AAV-mediated expression of human VEGF-A as a novel rat model of diabetic retinopathy

被引：0
|
作者：
Lelyte, Inesa [1 ,2 ]
Ragauskas, Symantas [3 ]
Paulauskas, Tomas [3 ]
Ahmed, Zubair [2 ]
Kaja, Simon [4 ,5 ]
Kalesnykas, Giedrius [1 ,3 ]
机构：
[1] Experiment Ltd, R&D Div, Kuopio, Finland
[2] Univ Birmingham, Inst Inflammat & Ageing, Birmingham, England
[3] Experiment Ltd, R&D Div, Vilnius, Lithuania
[4] Loyola Univ Chicago, Dept Ophthalmol, Chicago, IL USA
[5] Loyola Univ Chicago, Dept Mol Pharmacol & Neurosci, Chicago, IL USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2023年 / 64卷 / 08期
基金：
欧盟地平线“2020”;
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] AAV-mediated PEDF gene transfer to a transgenic mouse model of diabetic retinopathy
    Haurigot, Virginia
    Villacampa, Pilar
    Ribera, Albert
    Ramos, David
    Assumpcio, Bosch
    Ruberte, Jesus
    Bosch, Fatima
    HUMAN GENE THERAPY, 2008, 19 (10) : 1128 - 1128
  • [2] AAV-mediated expression of VEGF peptides inhibits retinal neovascularization (NV) in a mouse model of retinopathy of prematurity (ROP)
    Deng, W
    Yan, Z
    Berns, KI
    Hauswirth, WW
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 : U196 - U196
  • [3] Increased expression of VEGF receptors, KDR and FLT-4 in human diabetic retinopathy and in VEGF-A induced retinopathy in monkeys
    Witmer, AN
    Wetch, HA
    Partanen, TA
    Vrensen, GFJM
    Blaauwgeers, HGT
    Schlingemann, RO
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S702 - S702
  • [4] Role of VEGF-A in endothelial phenotypic shift in human diabetic retinopathy and VEGF-A-induced retinopathy in monkeys
    Hofman, P
    Blaauwgeers, HGT
    Vrensen, GFJM
    Schlingemann, RO
    OPHTHALMIC RESEARCH, 2001, 33 (03) : 156 - 162
  • [5] Recovery kinetics of dual AAV-mediated human otoferlin expression
    Sellon, Jonathan B.
    So, Kathy S.
    D'Arcangelo, Andrew
    Cancelarich, Sarah
    Drummond, Meghan C.
    Slade, Peter G.
    Pan, Ning
    Gibson, Tyler M.
    Yang, Tian
    Burns, Joseph C.
    Palermo, Adam T.
    Becker, Lars
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2024, 17
  • [6] EX VIVO AAV-MEDIATED GENE EXPRESSION IN THE HUMAN RETINA
    Orlans, H. O.
    Edwards, T. L.
    Patricio, M., I
    MacLaren, R. E.
    EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2017, 27 (02) : E78 - E78
  • [7] AAV-mediated gene transfer of ACE2 protects retinal vascular dysfunction in an animal model of diabetic retinopathy
    Li, Q.
    Shan, Z.
    Yuan, L.
    Miller, R.
    Lewin, A.
    Hauswirth, W.
    Raizada, M.
    JOURNAL OF HYPERTENSION, 2008, 26 : S329 - S329
  • [8] AAV-Mediated Expression of Human VEGF, TNF-a, and IL-6 Induces Retinal Pathology inMice
    Weigelt, Carina M.
    Fuchs, Holger
    Schoenberger, Tanja
    Stierstorfer, Birgit
    Strobel, Benjamin
    Lamla, Thorsten
    Ciossek, Thomas
    Bakker, Remko A.
    Redemann, Norbert H.
    TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2021, 10 (11):
  • [9] Expression of eNOS and VEGF in Normoxia Mediated Vasculopathy in Rat Retinopathy of Prematurity Model
    Hosseini, Alireza
    Lattanzio, Frank
    Eh, Nazita Youse
    Wade, Ryan
    Jacot, Jorge
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [10] Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson's disease - Validation of novel fine motor functional effects
    Pussinen, R.
    Ahtoniemi, T.
    Huhtala, T.
    Kontkanen, O.
    Nurmi, A.
    MOVEMENT DISORDERS, 2016, 31 : S427 - S427
12345