Absence of Zika virus among pregnant women in Vietnam in 2008 (vol 9, 4, 2023)

被引:0
|
作者
Chiu, Y. -c. [1 ]
Baud, D. [1 ,2 ]
Fahmi, A. [3 ,4 ,5 ]
Zumkehr, B. [3 ,4 ]
Vouga, M. [1 ]
Pomar, L. [1 ]
Musso, D. [6 ,7 ,8 ]
Thuong, B. C. [9 ]
Alves, M. P. [3 ,4 ,10 ]
Stojanov, M. [1 ,2 ]
机构
[1] Lausanne Univ Hosp, Dept Woman Mother Child, Materno Fetal & Obstet Res Unit, Lausanne, Switzerland
[2] Univ Lausanne, Fac Biol & Med, Lausanne, Switzerland
[3] Inst Virol & Immunol, Bern, Switzerland
[4] Univ Bern, Vetsuisse Fac, Dept Infect Dis & Pathobiol, Bern, Switzerland
[5] Univ Bern, Grad Sch Cellular & Biomed Sci, Bern, Switzerland
[6] Aix Marseille Univ, Assistance Publ Hop Marseille, Inst Rech Dev IRD, Serv Sante Armees,Vecteurs Infect Trop & Mediterra, Marseille, France
[7] Inst Hosp Univ Mediterranee Infect, Marseille, France
[8] Eurofins, Lab Eurofins Labazur Guyane, Cayenne, French Guiana
[9] Tu Hosp, Dist 1, Ho Chi Minh City, Vietnam
[10] Univ Bern, Multidisciplinary Ctr Infect Dis MCID, Bern, Switzerland
基金
瑞士国家科学基金会;
关键词
Infection; Placenta; Serology; Vietnam; Zika virus;
D O I
10.1186/s40794-023-00191-z
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Despite being first identified in 1947, Zika virus-related outbreaks were first described starting from 2007 culminating with the 2015 Latin American outbreak. Hypotheses indicate that the virus has been circulating in Asia for decades, but reports are scarce. Methods: We performed serological analysis and screened placental samples isolated in 2008 for the presence of Zika virus from pregnant women in Ho Chi Minh City (Vietnam). Results: None of the placental samples was positive for Zika virus. Four serum samples out of 176 (2.3%) specifically inhibited Zika virus, with variable degrees of cross-reactivity with other flaviviruses. While one of the four samples inhibited only Zika virus, cross-reactivity with other flaviviruses not included in the study could not be ruled out. Conclusion: Our results support the conclusion that the virus was not present among pregnant women in the Vietnamese largest city during the initial phases of the epidemic wave. © 2023, The Author(s).
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页数:1
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