Metal-free dearomative 2,3-difunctionalization of indoles via radical cascade

被引：2
|
作者：
Pal, Pranesh [1 ,2 ]
Goud, Gadela Karteek [1 ,2 ]
Sridhar, Balasubramanian [2 ,3 ]
Mainkar, Prathama S. [1 ,2 ]
Nayani, Kiranmai [1 ,2 ]
Chandrasekhar, Srivari [1 ,2 ]
机构：
[1] CSIR Indian Inst Chem Technol CSIR IICT, Dept Organ Synth & Proc Chem, Hyderabad 500007, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
[3] CSIR Indian Inst Chem Technol, Dept Analyt & Struct Chem, Hyderabad 500007, India
来源：
TETRAHEDRON LETTERS | 2023年 / 121卷
关键词：
Dearomatization; Difunctionalization; Metal-free; Indolines; Diastereoselective; SELENIUM; AZIDATION; DIAZIDATION; BONDS;
D O I：
10.1016/j.tetlet.2023.154478
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An oxidative dearomatization of protected indoles leading to 2-azido 3-arylselenyl indolines has been developed under metal-free conditions. The formation of C-N and C-Se bonds is believed to arise from the oxidation of indole via radical cascade. The reaction is regio and diastereo-selective and works under mild conditions.(c) 2023 Elsevier Ltd. All rights reserved.
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页数：5
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