Gut Microbiota and Neonatal Acute Kidney Injury

被引：0
|
作者：
Yang, Kun [1 ,2 ,3 ]
He, Hongxia [1 ,2 ,3 ]
Dong, Wenbin [1 ,2 ,3 ,4 ]
机构：
[1] Southwest Med Univ, Dept Pediat, Div Neonatol, Affiliated Hosp, Luzhou, Peoples R China
[2] Southwest Med Univ, Dept Perinatol, Affiliated Hosp, Luzhou, Peoples R China
[3] Sichuan Clin Res Ctr Birth Defects, Luzhou, Peoples R China
[4] Southwest Med Univ, Dept Pediat, Div Neonatol, Affiliated Hosp, Luzhou 646600, Peoples R China
来源：
AMERICAN JOURNAL OF PERINATOLOGY | 2024年 / 41卷 / 14期
基金：
中国国家自然科学基金;
关键词：
gut microbiota; neonatal acute kidney injury; gut-kidney axis; biomarkers; ENDOTHELIAL GROWTH-FACTOR; CHAIN FATTY-ACIDS; INTESTINAL MICROBIOTA; URINARY CLUSTERIN; EARLY-DIAGNOSIS; TUBULAR INJURY; UREMIC TOXINS; BIOMARKERS; GHRELIN; EXPRESSION;
D O I：
10.1055/a-2259-0101
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective To characterize the relationship between gut microbiota and neonatal acute kidney injury biomarkers based on the gut-kidney axis. Study Design The Pubmed database was primarily searched to include relevant literature on gut microbiota and neonatal acute kidney injury biomarkers, which was subsequently organized and analyzed and a manuscript was written. Results Gut microbiota was associated with neonatal acute kidney injury biomarkers. These biomarkers included TIMP-2, IGFBP-7, VEGF, calbindin, GST, B2MG, ghrelin, and clusterin. Conclusion The gut microbiota is strongly associated with neonatal acute kidney injury biomarkers, and controlling the gut microbiota may be a potential target for ameliorating neonatal acute kidney injury.
引用
收藏
页码：1887 / 1894
页数：8
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