Enaminone-directed ruthenium(II)-catalyzed C-H activation and annulation of arenes with diazonaphthoquinones for polycyclic benzocoumarins

被引：9
|
作者：
Mondal, Sudeshna [1 ]
Giri, Chandan Kumar [1 ]
Baidya, Mahiuddin [1 ]
机构：
[1] Indian Inst Technol Madras, Dept Chem, Chennai 600036, Tamil Nadu, India
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 88期
关键词：
BOND ACTIVATION; DIAZO-COMPOUNDS; CYCLOADDITION; CLEAVAGE; ALKYNES;
D O I：
10.1039/d3cc03999d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The weakly coordinating enaminone functionality has been leveraged for a C-H bond activation strategy under ruthenium catalysis and employed in the regioselective annulative coupling of arenes with diazonaphthoquinones, offering polycyclic benzocoumarins in very high yields. The enaminone motif plays a dual role and the protocol operates through a Ru(II)/Ru(IV) catalytic pathway which is amenable to the diversification of various pharmacophore-coupled substrates.
引用
收藏
页码：13187 / 13190
页数：4
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