Iron-Catalyzed Oxyphosphorylation of Styrenes to Access β-Ketophosphonates and α, β-Unsaturated Ketones

The first iron-catalyzed oxophosphorylation of styrene derivatives with dialkyl H-phosphonates under open air conditions is developed, which generates a range of previously underexplored asubstituted beta-ketophosphonates in 55 similar to 70% yields. Furthermore, a convenient one-pot procedure by direct conversion of styrenes to alpha, beta-unsaturated ketones is also developed based on the new catalytic reactions, thus offering a protocol to access two classes of valuable products from simple starting materials.