A Case of Varicella Zoster and Mpox Coinfection in a Patient Living With HIV

In patients with poorly controlled HIV, it is important to maintain a high index of suspicion for mpox and coinfection with other cutaneous diseases for clinical and diagnostic purposes. We present a case of recurrent, cutaneous mpox with coinfection of disseminated varicella zoster in an immunocompromised patient with poorly controlled HIV. This case demonstrates the importance of maintaining a high index of suspicion for mpox despite prior infection and vaccination, as suboptimal immune response is possible in immunocompromised patients, and also noting the potential for coinfection necessitating timely diagnosis and appropriate testing.