Efficacy and safety of the combination of encorafenib and cetuximab in patients with BRAF V600E mutated metastatic colorectal cancer: An AGEO real-world multicentre study

被引:2
|
作者
Gallois, C. [1 ]
Elez Fernandez, M. E. [2 ]
Auclin, E. [3 ]
Bergen, E. S. [4 ]
Pernot, S. [5 ]
Higue, J. [6 ]
Trouilloud, I. [7 ]
Touchefeu, Y. [8 ]
Turpin, A. [9 ]
Mazard, T. [10 ]
Pilla, L. [1 ]
Cuissy, S. [11 ]
Wookey, V. [12 ]
Perret, A. [13 ]
Melchior, C. [14 ]
Artru, P. [15 ]
Stintzing, S. [16 ]
Dubreuil, O. [17 ]
Tougeron, D. [18 ]
Taieb, J. [19 ]
机构
[1] Hop Europeen Georges Pompidou, AP HP, Digest Oncol Dept, Paris, France
[2] Vall dHebron Univ Hosp, Dept Med Oncol, Barcelona, Spain
[3] Hop Europeen Georges Pompidou, AP HP, Oncol Dept, Paris, France
[4] Univ Kliniken MedUni Wien AKH Wien, Div Oncol, Dept Med 1, Vienna, Austria
[5] Inst Bergonie, Digest Med Oncol Unit, Bordeaux, France
[6] Inst Univ Canc Toulouse Oncopole, Haute Garonne, Toulouse, France
[7] Hop St Antoine, Med Oncol Dept, Paris, France
[8] CHU Nantes, Digest Oncol, Hotel Dieu, Nantes, France
[9] CHU Lille, Dept Med Oncol, Lille, France
[10] Inst Canc Montpellier, Med Oncol, Montpellier, France
[11] CHU Rouen Normandie, Seine Maritime, Rouen, France
[12] Mayo Clin, Dept Oncol, Rochester, MN USA
[13] Inst Gustave Roussy, Digest Oncol Dept, Villejuif, France
[14] Ctr Leon Berard, Digest Oncol Dept, Lyon, France
[15] Hop Prive Jean Mermoz, GI Oncol Dept, Lyon, France
[16] Charite Univ Med Berlin, Hematol Oncol & Canc Immunol CCM Dept, Berlin, Germany
[17] Gh Diaconesses Croix St Simon, Med Oncol, Paris, France
[18] CHU Poitiers, Dept Gastroenterol & Hepatol, Jean Bernard Hop, Poitiers, France
[19] Hop European George Pompidou, Gastroenterol & Digest Oncol Dept, Paris, France
关键词
D O I
10.1016/j.annonc.2023.09.1816
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
625P
引用
收藏
页码:S446 / S446
页数:1
相关论文
共 50 条
  • [1] Efficacy and safety of the combination of encorafenib/cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: an AGEO real-world multicenter study
    Gallois, C.
    Bergen, E. S.
    Auclin, E.
    Pernot, S.
    Higue, J.
    Trouilloud, I.
    Touchefeu, Y.
    Turpin, A.
    Mazard, T.
    Sartore-Bianchi, A.
    Prenen, H.
    Alberti, A.
    Pilla, L.
    Cuissy, S.
    Wookey, V.
    Perret, A.
    Melchior, C.
    Artru, P.
    Dubreuil, O.
    Drouillard, A.
    Doat, S.
    Lavole, J.
    Basile, D.
    Perkins, G.
    Jary, M.
    Stintzing, S.
    Jos, J.
    Tougeron, D.
    Taieb, J.
    ESMO OPEN, 2024, 9 (09)
  • [2] Safety of encorafenib, binimetinib, plus cetuximab for Japanese patients with BRAF V600E metastatic colorectal cancer
    Yamaguchi, Toshifumi
    Daisuke, Kotani
    Atsuo, Takashima
    Takeshi, Kato
    Toshiki, Masuishi
    Yoshito, Komatsu
    Manabu, Shiozawa
    Taito, Esaki
    Naoki, Izawa
    Shinji, Takeuchi
    Hideaki, Bando
    Satoru, Iwasa
    Hiroko, Hasegawa
    Taroh, Satoh
    Hiroya, Taniguchi
    Takayuki, Yoshino
    ANNALS OF ONCOLOGY, 2022, 33 : S479 - S479
  • [3] A phase II study of daily encorafenib in combination with biweekly cetuximab in patients with BRAF V600E mutated metastatic colorectal cancer: the NEW BEACON study
    Martina Eriksen
    Per Pfeiffer
    Kristoffer Staal Rohrberg
    Christina Westmose Yde
    Lone Nørgård Petersen
    Laurids Østergaard Poulsen
    Camilla Qvortrup
    BMC Cancer, 22
  • [4] A phase II study of daily encorafenib in combination with biweekly cetuximab in patients with BRAF V600E mutated metastatic colorectal cancer: the NEW BEACON study
    Eriksen, Martina
    Pfeiffer, Per
    Rohrberg, Kristoffer Staal
    Yde, Christina Westmose
    Petersen, Lone Norgard
    Poulsen, Laurids Ostergaard
    Qvortrup, Camilla
    BMC CANCER, 2022, 22 (01)
  • [5] Encorafenib, binimetinib, and cetuximab combination therapy for patients with BRAF V600E mutant colorectal cancer
    Moro, Kazuki
    Saiki, Takuro
    Sasaki, Kenta
    Matsumoto, Akio
    Zhou, Qiliang
    Nakano, Mae
    Nakano, Masato
    Matsumoto, Yoshifumi
    Shimada, Yoshifumi
    Moriyama, Masato
    Wakai, Toshifumi
    Saijo, Yasuo
    ANNALS OF ONCOLOGY, 2022, 33 : S541 - S541
  • [6] Encorafenib and cetuximab in patients with metastatic, BRAF V600E-mutated, colorectal cancer: Update on the first real-world study in Germany and Austria BERING CRC
    von der Heyde, E.
    Buerkle, D.
    Forstbauer, H.
    Huebner, G.
    Schmidt, B.
    Schroeder, J.
    Distelrath, A.
    Wierecky, J.
    Stuebs, P.
    Kisro, J.
    Welslau, M.
    Mueller-Huesmann, H.
    Goehler, T.
    Krammer-Steiner, B.
    Schwaner, I.
    Hering-Schubert, C.
    Gerger, A.
    Greil, R.
    Jacobasch, L.
    Reichenbach, F.
    Stintzing, S.
    Prager, G.
    ANNALS OF ONCOLOGY, 2022, 33 : S248 - S248
  • [7] Encorafenib plus cetuximab for the treatment of BRAF-V600E-mutated metastatic colorectal cancer
    Ros, Javierd
    Saoudi, Nadia
    Baraibar, Iosune
    Salva, Francesc
    Tabernero, Josep
    Elez, Elena
    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2022, 15
  • [8] Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer
    Prasad, Vinay
    NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (09): : 876 - 876
  • [9] Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer
    Roviello, Giandomenico
    D'Angelo, Alberto
    Petrioli, Roberto
    Roviello, Franco
    Cianchi, Fabio
    Nobili, Stefania
    Mini, Enrico
    Lavacchi, Daniele
    TRANSLATIONAL ONCOLOGY, 2020, 13 (09):
  • [10] Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer
    Kopetz, S.
    Grothey, A.
    Yaeger, R.
    Van Cutsem, E.
    Desai, J.
    Yoshino, T.
    Wasan, H.
    Ciardiello, F.
    Loupakis, F.
    Hong, Y. S.
    Steeghs, N.
    Guren, T. K.
    Arkenau, H. -T.
    Garcia-Alfonso, P.
    Pfeiffer, P.
    Orlov, S.
    Lonardi, S.
    Elez, E.
    Kim, T. -W.
    Schellens, J. H. M.
    Guo, C.
    Krishnan, A.
    Dekervel, J.
    Morris, V.
    Calvo Ferrandiz, A.
    Tarpgaard, L. S.
    Braun, M.
    Gollerkeri, A.
    Keir, C.
    Maharry, K.
    Pickard, M.
    Christy-Bittel, J.
    Anderson, L.
    Sandor, V.
    Tabernero, J.
    NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (17): : 1632 - 1643