A PHENOME-WIDE ASSOCIATION STUDY OF POLYGENIC LIABILITY FOR EXTERNALIZING IN A EUROPEAN COHORT REVEALS SEX-SPECIFIC ASSOCIATIONS WITH NUMEROUS MEDICAL OUTCOMES

被引：0
|
作者：
Courchesne-Krak, Natasia [1 ]
Singh, Kritika [2 ]
Lake, Allison M. [2 ]
Jennings, Mariela [1 ]
Meredith, John [1 ]
Williams, Camille [3 ]
Mallard, Travis [4 ]
Barr, Peter [5 ]
Waldman, Irwin [6 ]
Palmer, Abraham [1 ]
Dick, Danielle [7 ]
Davis, Lea [2 ]
Sanchez-Roige, Sandra [1 ,2 ]
机构：
[1] Univ Calif San Diego, La Jolla, CA USA
[2] Vanderbilt Univ, Nashville, TN USA
[3] Univ Texas Austin, Austin, TX USA
[4] Harvard Med Sch, Massachusetts Gen Hosp, Ctr Genom Med, Boston, MA USA
[5] SUNY Downstate Hlth Sci Univ, VA New York Harbor Healthcare Syst, New York, NY USA
[6] Emory Univ, Atlanta, GA USA
[7] Rutgers State Univ, Piscataway, NJ USA
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2023年 / 75卷
关键词：
D O I：
10.1016/j.euroneuro.2023.08.284
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
W98
引用
收藏
页码：S156 / S157
页数：2
相关论文
共 22 条
  • [1] Phenome-wide associations of human aging uncover sex-specific dynamics
    Reicher, Lee
    Bar, Noam
    Godneva, Anastasia
    Reisner, Yotam
    Zahavi, Liron
    Shahaf, Nir
    Dhir, Raja
    Weinberger, Adina
    Segal, Eran
    NATURE AGING, 2024, 4 (11): : 1643 - +
  • [2] Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
    Isabelle M. McGrath
    Grant W. Montgomery
    Sally Mortlock
    BMC Medicine, 21
  • [3] Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
    Mcgrath, Isabelle M.
    Montgomery, Grant W.
    Mortlock, Sally
    BMC MEDICINE, 2023, 21 (01)
  • [4] POLYGENIC LIABILITY TO DEPRESSION IS ASSOCIATED WITH MULTIPLE MEDICAL CONDITIONS IN THE ELECTRONIC HEALTH RECORD: PHENOME-WIDE ASSOCIATION STUDY OF 46,782 INDIVIDUALS
    Fang, Yu
    Fritsche, Lars G.
    Mukherjee, Bhramar
    Sen, Srijan
    Richmond-Rakerd, Leah S.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2022, 63 : E76 - E76
  • [5] Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
    Pritesh Jain
    Tyne Miller-Fleming
    Apostolia Topaloudi
    Dongmei Yu
    Petros Drineas
    Marianthi Georgitsi
    Zhiyu Yang
    Renata Rizzo
    Kirsten R. Müller-Vahl
    Zeynep Tumer
    Nanette Mol Debes
    Andreas Hartmann
    Christel Depienne
    Yulia Worbe
    Pablo Mir
    Danielle C. Cath
    Dorret I. Boomsma
    Veit Roessner
    Tomasz Wolanczyk
    Piotr Janik
    Natalia Szejko
    Cezary Zekanowski
    Csaba Barta
    Zsofia Nemoda
    Zsanett Tarnok
    Joseph D. Buxbaum
    Dorothy Grice
    Jeffrey Glennon
    Hreinn Stefansson
    Bastian Hengerer
    Noa Benaroya-Milshtein
    Francesco Cardona
    Tammy Hedderly
    Isobel Heyman
    Chaim Huyser
    Astrid Morer
    Norbert Mueller
    Alexander Munchau
    Kerstin J. Plessen
    Cesare Porcelli
    Susanne Walitza
    Anette Schrag
    Davide Martino
    Andrea Dietrich
    Carol A. Mathews
    Jeremiah M. Scharf
    Pieter J. Hoekstra
    Lea K. Davis
    Peristera Paschou
    Translational Psychiatry, 13
  • [6] Polygenic Liability to Depression Is Associated With Multiple Medical Conditions in the Electronic Health Record: Phenome-wide Association Study of 46,782 Individuals
    Fang, Yu
    Fritsche, Lars G.
    Mukherjee, Bhramar
    Sen, Srijan
    Richmond-Rakerd, Leah S.
    BIOLOGICAL PSYCHIATRY, 2022, 92 (12) : 923 - 931
  • [7] Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
    Jain, Pritesh
    Miller-Fleming, Tyne
    Topaloudi, Apostolia R.
    Yu, Dongmei K.
    Drineas, Petros
    Georgitsi, Marianthi
    Yang, Zhiyu
    Rizzo, Renata
    Mueller-Vahl, Kirsten R.
    Tumer, Zeynep A.
    Mol Debes, Nanette
    Hartmann, Andreas S.
    Depienne, Christel E.
    Worbe, Yulia S.
    Mir, Pablo
    Cath, Danielle C.
    Boomsma, Dorret, I
    Roessner, Veit
    Wolanczyk, Tomasz
    Janik, Piotr
    Szejko, Natalia
    Zekanowski, Cezary
    Barta, Csaba
    Nemoda, Zsofia
    Tarnok, Zsanett
    Buxbaum, Joseph D.
    Grice, Dorothy
    Glennon, Jeffrey
    Stefansson, Hreinn
    Hengerer, Bastian
    Benaroya-Milshtein, Noa
    Cardona, Francesco
    Hedderly, Tammy
    Heyman, Isobel
    Huyser, Chaim
    Morer, Astrid
    Mueller, Norbert
    Munchau, Alexander
    Plessen, Kerstin J.
    Porcelli, Cesare
    Walitza, Susanne
    Schrag, Anette
    Martino, Davide
    Dietrich, Andrea
    Mathews, Carol A.
    Scharf, Jeremiah M.
    Hoekstra, Pieter J.
    Davis, Lea K.
    Paschou, Peristera
    TRANSLATIONAL PSYCHIATRY, 2023, 13 (01)
  • [8] A phenome-wide association study of cross-disorder genetic liability in youth genetically similar to individuals from European reference populations
    Sarah E. Paul
    Sarah M. C. Colbert
    Aaron J. Gorelik
    Emma C. Johnson
    Alexander S. Hatoum
    David A. A. Baranger
    Isabella S. Hansen
    I. Nagella
    L. Blaydon
    A. Hornstein
    Nourhan M. Elsayed
    Deanna M. Barch
    Ryan Bogdan
    Nicole R. Karcher
    Nature Mental Health, 2024, 2 (11): : 1327 - 1341
  • [9] Phenome-wide Study of Electronic Medical Record Data Reveals Novel Association of Natriuretic Peptide A Genetic Variant With Rheumatoid Arthritis
    Pereira, Naveen
    Jenkins, Gregory
    Kullo, Ifthikar
    Bielinski, Suzette
    Burnett, John
    Pathak, Jyotishman
    CIRCULATION, 2015, 132
  • [10] PHENOME-WIDE ASSOCIATION STUDY OF SMOKING AND CAFFEINE USE ON MENTAL HEALTH OUTCOMES USING DATA FROM THE ALSPAC PREGNANCY COHORT
    Haan, Elis
    Schellhas, Laura
    Sallis, Hannah
    Munafo, Marcus
    Zuccolo, Luisa
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2019, 29 : S17 - S17
123