D02, a novel, non-blocking antibody targeting IL2RA, exhibits significant anti-tumor activity in IL2RA-humanized mice

被引:0
|
作者
Cao, Shuzhen
Zhang, Wenjiao
Lin, Qingcong
机构
关键词
D O I
10.1158/1538-7445.AM2023-1866
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1866
引用
收藏
页数:2
相关论文
共 6 条
  • [1] 1C3, a Novel non-blocking anti-human TNFR2 antibody generated from RenMice, exhibits promising anti-tumor activity and safety in syngeneic tumor models in humanized TNFR2 mice
    Yang, Yongfei
    Cao, Shuzhen
    Zhang, Jing
    Shao, Zhe
    Jiang, Xueyuan
    Duan, Qingya
    Tian, Maopeng
    Mei, Sen
    Yu, Luke
    CANCER RESEARCH, 2022, 82 (12)
  • [2] Therapy with a non-blocking monoclonal antibody targeting soluble NKG2D ligand MIC revamps endogenous innate and adaptive anti-tumor responses and eliminates primary and metastatic tumors
    Wu, Jennifer
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (01)
  • [4] A novel not-α IL-2 elicits potent anti-tumor activity in mice by improving the effector to regulatory T cell balance.
    Kobayashi, Maki
    Ogama, Naoko
    Kojima, Katsuhiko
    Fukuhara, Tatsuro
    Tanaka, Nobuyuki
    CANCER SCIENCE, 2022, 113
  • [5] A novel not-α IL-2 elicits potent anti-tumor activity in mice by improving the effector to regulatory T cell balance.
    Kobayashi, Maki
    Ogama, Naoko
    Kojima, Katsuhiko
    Fukuhara, Tatsuro
    Tanaka, Nobuyuki
    CANCER SCIENCE, 2021, 112 : 390 - 390
  • [6] Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model
    Sophiya, P.
    Urs, Deepadarshan
    K. Lone, Jafar
    Giresha, A. S.
    Krishna Ram, H.
    Manjunatha, J. G.
    El-Serehy, Hamed A.
    Narayanappa, M.
    Shankar, J.
    Bhardwaj, Ragini
    Ahmad Guru, Sameer
    Dharmappa, K. K.
    FRONTIERS IN PHARMACOLOGY, 2022, 13