Grevillosides R-S: glucosides of 5-alkylresorcinol derivatives from roots of Ardisia crispa (Thunb.) A. DC

被引：2
|
作者：
Long, Xing-xiang [1 ]
Zhang, Shuang [1 ]
Xiang, Li-juan [1 ]
Hu, Rui-hang [1 ]
Feng, Ting-ting [1 ]
Zhou, Ying [1 ]
Yin, Xin [1 ]
机构：
[1] Guizhou Univ Tradit Chinese Med, Coll Pharm, Guiyang, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2025年 / 39卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Primulaceae; Ardisia crispa (Thunb.) A. DC; 5-alkylresorcinol derivatives; antioxidant activity; alpha-glucosidase inhibitory activity;
D O I：
10.1080/14786419.2023.2258545
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Grevillosides R-S (1-2), two new glucosides of 5-alkylresorcinol derivatives, were isolated from the roots of Ardisia crispa (Thunb.) A. DC. The structures of grevillosides R-S (1-2) were determined by 1D and 2D NMR, HR-MS, UV, IR experiments and by comparison of their spectroscopic and physical data with literature values. In this paper, grevillosides R-S (1-2) were tested for their radical-scavenging activity (DPPH and ABTS) and alpha-glucosidase inhibitory activity in vitro. Grevillosides R-S (1-2) exhibited weak DPPH radical-scavenging activity with IC50 values of 72.3 and 485.2 mu M, respectively. Grevillosides R-S (1-2) exhibited no inhibitory activity against alpha-glucosidase. [GRAPHICS] .
引用
收藏
页码：157 / 162
页数：6
相关论文
共 7 条
  • [1] Grevillosides A-F: Glucosides of 5-alkylresorcinol derivatives from leaves of Grevillea robusta
    Yamashita, Yukiko
    Matsunami, Katsuyoshi
    Otsuka, Hideaki
    Shinzato, Takakazu
    Takeda, Yoshio
    PHYTOCHEMISTRY, 2008, 69 (15) : 2749 - 2752
  • [2] The hexane fraction of Ardisia crispa Thunb. A. DC. roots inhibits inflammation-induced angiogenesis
    Hamsin, Dayang Erna Zulaikha Awang
    Hamid, Roslida Abdul
    Yazan, Latifah Saiful
    Taib, Che Norma Mat
    Ting, Yeong Looi
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 13
  • [3] The hexane fraction of Ardisia crispa Thunb. A. DC. roots inhibits inflammation-induced angiogenesis
    Dayang Erna Zulaikha Awang Hamsin
    Roslida Abdul Hamid
    Latifah Saiful Yazan
    Che Norma Mat Taib
    Yeong Looi Ting
    BMC Complementary and Alternative Medicine, 13
  • [4] Quinone-rich fraction of Ardisia crispa (Thunb.) A. DC roots alters angiogenic cascade in collagen-induced arthritis
    Blin, Joan Anak
    Ali, Razana Mohd
    Nurdin, Armania
    Abd Hamid, Roslida
    INFLAMMOPHARMACOLOGY, 2021, 29 (03) : 771 - 788
  • [5] Quinone-rich fraction of Ardisia crispa (Thunb.) A. DC roots alters angiogenic cascade in collagen-induced arthritis
    Joan Anak Blin
    Razana Mohd Ali
    Armania Nurdin
    Roslida Abd Hamid
    Inflammopharmacology, 2021, 29 : 771 - 788
  • [6] Anti-fungal activity of Ardisia crispa (Thunb.) A.DC. against several fungi responsible for athlete's foot
    Somchit, M. N.
    Adam, Y.
    Yee, H. C.
    Zuraini, A.
    Arifah, A. K.
    Zakaria, Z. A.
    AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH, 2011, 5 (15): : 2008 - 2010
  • [7] A 1, 4-benzoquinone derivative isolated from Ardisia crispa (Thunb.) A. DC. root suppresses angiogenesis via its angiogenic signaling cascades
    Lim, Wen Jun
    Chan, Pit Foong
    Abd Hamid, Roslida
    SAUDI PHARMACEUTICAL JOURNAL, 2024, 32 (01)
1