Ventriculomegaly is a marker of abnormal brain development and is a cause for concern when present. It has a prevalence of 0.3-1/1000 live births and is more frequent in male fetuses. Ventriculomegaly is defined as the atrioventricular diameter of the lateral ventricles greater than or equal to 10 mm. A measurement of 10-15 mm constitutes mild ventriculomegaly while values >15 mm constitute severe ventriculomegaly. Ventriculomegaly may be isolated or associated with other anomalies including abnormal structural findings, chromosomal abnormalities or prenatal infections in about 50-84% of cases. If ventriculomegaly is mild and isolated, the most frequent outcome is normal. Survival of newborns with isolated mild ventriculomegaly is high, with reports of 93-98%. The probability of normal neurodevelopment is greater than 90% and will not be different from that of the general population. Therefore, in the presence of isolated mild ventriculomegaly, after a complete evaluation, the pregnant woman should be informed that the prognosis is favorable, and that the child will probably be considered normal. We present a case of isolated mild left ventriculomegaly detected in the prenatal ultrasound at 20 weeks, who underwent serial neurosonographic controls, genetic amniocentesis and study of prenatal infections, the latter two being normal and showing resolution of ventriculomegaly, as well as postpartum control within the limits of normality.
机构:Birmingham Heartlands Hosp, Neonatol Unit, Birmingham B9 5SS, W Midlands, England
Wyldes, M
Watkinson, M
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Birmingham Heartlands Hosp, Neonatol Unit, Birmingham B9 5SS, W Midlands, EnglandBirmingham Heartlands Hosp, Neonatol Unit, Birmingham B9 5SS, W Midlands, England
Watkinson, M
[J].
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION,
2004,
89
(01):
: F9
-
F13
机构:Univ London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, England
Melchiorre, K.
Bhide, A.
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机构:Univ London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, England
Bhide, A.
Gika, A. D.
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Evelina Childrens Hosp, Guys & St Thomas NHS Fdn Trust, Dept Paediat Neurol, London, EnglandUniv London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, England
Gika, A. D.
Pilu, G.
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Univ Bologna, Dept Obstet & Gynecol, Bologna, ItalyUniv London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, England
Pilu, G.
Papageorghiou, A. T.
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Univ London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, EnglandUniv London St Georges Hosp, Sch Med, Fetal Med Unit, Acad Dept Obstet & Gynaecol, London SW17 0RE, England
机构:
Chinese Univ Hong Kong, Dept Obstet & Gynaecol, Fetal Med Unit, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Obstet & Gynaecol, Fetal Med Unit, Hong Kong, Hong Kong, Peoples R China
Chan, L. W.
Lau, T. K.
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Chinese Univ Hong Kong, Dept Obstet & Gynaecol, Fetal Med Unit, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Obstet & Gynaecol, Fetal Med Unit, Hong Kong, Hong Kong, Peoples R China
机构:
St George Hosp, Sch Med, Dept Obstet & Gynaecol, Fetal Med Unit, London, EnglandSt George Hosp, Sch Med, Dept Obstet & Gynaecol, Fetal Med Unit, London, England
Melchiorre, K.
Papageorghiou, A. T.
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St George Hosp, Sch Med, Dept Obstet & Gynaecol, Fetal Med Unit, London, EnglandSt George Hosp, Sch Med, Dept Obstet & Gynaecol, Fetal Med Unit, London, England
机构:
Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Vasung, Lana
Rollins, Caitlin K.
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Harvard Med Sch, Boston Childrens Hosp, Dept Neurol Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Rollins, Caitlin K.
Zhang, Jennings
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Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Zhang, Jennings
Velasco-Annis, Clemente
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Velasco-Annis, Clemente
Yang, Edward
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Yang, Edward
Lin, Ivy
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Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Lin, Ivy
Sutin, Jason
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Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Sutin, Jason
Warfield, Simon Keith
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Warfield, Simon Keith
Soul, Janet
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Harvard Med Sch, Boston Childrens Hosp, Dept Neurol Med, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Soul, Janet
Estroff, Judy
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USA
Boston Childrens Hosp, Maternal Fetal Care Ctr, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Estroff, Judy
Connolly, Susan
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USA
Boston Childrens Hosp, Maternal Fetal Care Ctr, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Connolly, Susan
Barnewolt, Carol
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USA
Boston Childrens Hosp, Maternal Fetal Care Ctr, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Barnewolt, Carol
Gholipour, Ali
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Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Gholipour, Ali
Feldman, Henry A.
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Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Med Sch, Inst Ctr Clin & Translat Res, Boston Childrens Hosp, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Feldman, Henry A.
Grant, Patricia Ellen
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Harvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Med Sch, Boston Childrens Hosp, Dept Radiol, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA