Murine Hepatitis Virus Exoribonuclease nsp14 Is Required for the Biogenesis of Viral Circular RNAs

被引:4
|
作者
Yang, Shaomin [1 ,2 ]
Cruz-Cosme, Ruth [3 ]
Cao, Di [1 ,2 ]
Zhou, Hong [3 ]
Wu, Songbin [4 ]
Huang, Jiabin [4 ]
Luo, Zhen [1 ,2 ]
Zhu, Hua [5 ]
Tang, Qiyi [3 ]
机构
[1] Huazhong Univ Sci & Technol, Union Shenzhen Hosp, Dept Pain Med, Shenzhen, Peoples R China
[2] Huazhong Univ Sci & Technol, Union Shenzhen Hosp, Shenzhen Municipal Key Lab Pain Med, Shenzhen, Peoples R China
[3] Howard Univ, Coll Med, Washington, DC 20059 USA
[4] Shenzhen Univ Hlth Sci Ctr, Shenzhen Nanshan Peoples Hosp, Shenzhen, Peoples R China
[5] Rutgers State Univ, Newark, NJ 07103 USA
来源
MICROBIOLOGY SPECTRUM | 2023年 / 11卷 / 03期
基金
美国国家卫生研究院;
关键词
murine hepatitis virus; nsp14; circRNA; RNA splice junction;
D O I
10.1128/spectrum.04460-22
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页数:5
相关论文
共 50 条
  • [1] Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity
    Case, James Brett
    Li, Yize
    Elliott, Ruth
    Lu, Xiaotao
    Graepel, Kevin W.
    Sexton, Nicole R.
    Smith, Everett Clinton
    Weiss, Susan R.
    Denison, Mark R.
    JOURNAL OF VIROLOGY, 2018, 92 (01)
  • [2] High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants
    Eckerle, Lance D.
    Lu, Xiaotao
    Sperry, Steven M.
    Choi, Leena
    Denison, Mark R.
    JOURNAL OF VIROLOGY, 2007, 81 (22) : 12135 - 12144
  • [3] Effects of mutagenesis of murine hepatitis virus Nsp1 and Nsp14 on replication in culture
    Eckerle, Lance D.
    Brockway, Sarah M.
    Sperry, Steven M.
    Lu, Xiaotao
    Denison, Mark R.
    NIDOVIRUSES: TOWARD CONTROL OF SARS AND OTHER NIDOVIRUS DISEASES, 2006, 581 : 55 - 60
  • [4] The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity
    Grimes, Samantha L.
    Heaton, Brook E.
    Anderson, Mackenzie L.
    Burke, Katie
    Stevens, Laura
    Lu, Xiaotao
    Heaton, Nicholas S.
    Denison, Mark R.
    Anderson-Daniels, Jordan
    JOURNAL OF VIROLOGY, 2025, 99 (02)
  • [5] Crucial mutation in the exoribonuclease domain of nsp14 of PEDV leads to high genetic instability during viral replication
    Xiaoyu Niu
    Fanzhi Kong
    Yixuan J. Hou
    Qiuhong Wang
    Cell & Bioscience, 11
  • [6] Crucial mutation in the exoribonuclease domain of nsp14 of PEDV leads to high genetic instability during viral replication
    Niu, Xiaoyu
    Kong, Fanzhi
    Hou, Yixuan J.
    Wang, Qiuhong
    CELL AND BIOSCIENCE, 2021, 11 (01):
  • [7] Activation of the SARS-CoV-2 NSP14 3′-5′ exoribonuclease by NSP10 and response to antiviral inhibitors
    Riccio, Amanda A.
    Sullivan, Eric D.
    Copeland, William C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 298 (01)
  • [8] Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
    Canal, Berta
    McClure, Allison W.
    Curran, Joseph F.
    Wu, Mary
    Ulferts, Rachel
    Weissmann, Florian
    Zeng, Jingkun
    Bertolin, Agustina P.
    Milligan, Jennifer C.
    Basu, Souradeep
    Drury, Lucy S.
    Deegan, Tom D.
    Fujisawa, Ryo
    Roberts, Emma L.
    Basier, Clovis
    Labib, Karim
    Beale, Rupert
    Howell, Michael
    Diffley, John F. X.
    BIOCHEMICAL JOURNAL, 2021, 478 (01) : 2445 - 2464
  • [9] The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2
    Ogando, Natacha S.
    Zevenhoven-Dobbe, Jessika C.
    van der Meer, Yvonne
    Bredenbeek, Peter J.
    Posthuma, Clara C.
    Snijder, Eric J.
    JOURNAL OF VIROLOGY, 2020, 94 (23)
  • [10] Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs
    Narayanan, Naveen
    Nair, Deepak T.
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 168 : 272 - 278