Tails don't tell the whole story

被引：0
|
作者：
Garcia-Marcos, Mikel [1 ,2 ]
机构：
[1] Boston Univ, Chobanian & Avedisian Sch Med, Dept Biochem & Cell Biol, Boston, MA 02115 USA
[2] Boston Univ, Coll Arts & Sci, Dept Biol, Boston, MA 02115 USA
来源：
STRUCTURE | 2023年 / 31卷 / 05期
关键词：
PROTEINS; COMPLEX;
D O I：
10.1016/j.str.2023.03.015
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Before engaging G protein-coupled receptors (GPCRs) to transduce extracellular signals, heterotrimeric G proteins (G alpha beta gamma) must fold properly with the help of chaperones. In this issue of Structure, Papasergi-Scott et al. (2023) unveil the molecular basis for how mammalian Ric-8 chaperones achieve selectivity for their respective G alpha subunit clients.
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页码：505 / 506
页数：2
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