A fractional-order control model for diabetes with restraining and time-delay

被引:6
|
作者
Balakrishnan, Ganesh Priya [1 ]
Chinnathambi, Rajivganthi [2 ]
Rihan, Fathalla A. [3 ]
机构
[1] Mepco Schlenk Engn Coll, Dept Math, Sivakasi 626005, Tamil Nadu, India
[2] Vellore Inst Technol, Sch Adv Sci, Div Math, Chennai 600127, Tamilnadu, India
[3] United Arab Emirates Univ, Coll Sci, Dept Math Sci, Al Ain 15551, U Arab Emirates
关键词
Diabetes; Fractional-order; Optimal control; Stability; Time-delay; MATHEMATICAL-MODELS; SYSTEM;
D O I
10.1007/s12190-023-01885-5
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Even though diabetes is a silent killer and one of the world's leading public health issues, people can take preventative measures by becoming aware of its causes. This study aims to identify the importance of treatment function and then control the complications of various individuals. We present a mathematical model of diabetes (type-2 diabetes) based on insulin therapy as a controlling factor. With fractional-order delay differential equations, four parts of the population control the dynamic system. The well-posedness (positivity, boundedness) of the model is examined to show that it is biologically and mathematically relevant. According to the characteristics equations for the model, certain sufficient conditions must be met for diabetic-free, endemic equilibrium points to be stable locally. To assess the imbalanced glucose level and treatment over a finite time period, we construct an optimal control problem based on treatment control and awareness program control as time-dependent control parameters. A necessary and sufficient condition for optimality is examined. In order to determine the most cost-effective treatment strategy with limited resources, we assessed the effectiveness and costs of treatments. The theoretical findings are verified by numerical simulations.
引用
下载
收藏
页码:3403 / 3420
页数:18
相关论文
共 50 条
  • [1] A fractional-order control model for diabetes with restraining and time-delay
    Ganesh Priya Balakrishnan
    Rajivganthi Chinnathambi
    Fathalla A. Rihan
    Journal of Applied Mathematics and Computing, 2023, 69 : 3403 - 3420
  • [2] A fractional-order epidemic model with time-delay and nonlinear incidence rate
    Rihan, F. A.
    Al-Mdallal, Q. M.
    AlSakaji, H. J.
    Hashish, A.
    CHAOS SOLITONS & FRACTALS, 2019, 126 (97-105) : 97 - 105
  • [3] Synchronisation and Circuit Model of Fractional-Order Chaotic Systems with Time-Delay
    Atan, Ozkan
    IFAC PAPERSONLINE, 2016, 49 (29): : 68 - 72
  • [4] Chaotic Dynamics and Chaos Control in a Fractional-Order Satellite Model and Its Time-Delay Counterpart
    Sayed, Ahmed M.
    Matouk, A. E.
    Kumar, Sanjay
    Ali, Vakkar
    Bachioua, Lahcene
    DISCRETE DYNAMICS IN NATURE AND SOCIETY, 2021, 2021
  • [5] Stabilization of Fractional-Order Descriptor Time-Delay Systems
    Pakzad, Mohammad Ali
    2023 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS, ISCAS, 2023,
  • [6] Disturbance Rejection for Fractional-Order Time-Delay Systems
    Jiang, Hai-Peng
    Liu, Yong-Qiang
    MATHEMATICAL PROBLEMS IN ENGINEERING, 2016, 2016
  • [7] Design of Functional Fractional-Order Observers for Linear Time-Delay Fractional-Order Systems in the Time Domain
    Boukal, Y.
    Darouach, M.
    Zasadzinski, M.
    Radhy, N. E.
    2014 INTERNATIONAL CONFERENCE ON FRACTIONAL DIFFERENTIATION AND ITS APPLICATIONS (ICFDA), 2014,
  • [8] Smith predictor based fractional-order PI control for time-delay processes
    Truong Nguyen Luan Vu
    Moonyong Lee
    Korean Journal of Chemical Engineering, 2014, 31 : 1321 - 1329
  • [9] Event-triggered H∞ control for fractional-order time-delay systems
    Huong, Dinh Cong
    ASIAN JOURNAL OF CONTROL, 2024,
  • [10] Robust stabilization of interval fractional-order plants with one time-delay by fractional-order controllers
    Gao, Zhe
    JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS, 2017, 354 (02): : 767 - 786