Sequencing-based methods for single-cell multi-omics studies

被引：0
|
作者：
Qin, Shanshan [1 ,2 ]
Liu, Songmei [1 ]
Weng, Xiaocheng [1 ,2 ]
机构：
[1] Wuhan Univ, Ctr Gene Diag, Dept Clin Lab, Program Clin Lab Med,Zhongnan Hosp, Wuhan 430072, Peoples R China
[2] Wuhan Univ, Coll Chem & Mol Sci, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Peoples R China
来源：
SCIENCE CHINA-CHEMISTRY | 2023年 / 66卷 / 11期
基金：
中国国家自然科学基金;
关键词：
single-cell multi-omics; multimodal studies; sequencing methods; CONTIGUITY-PRESERVING TRANSPOSITION; MOUSE EARLY EMBRYOS; RNA-SEQ; DNA METHYLATION; GENE-EXPRESSION; CHROMATIN ACCESSIBILITY; PROTEIN EXPRESSION; MESSENGER-RNA; GENOME; TRANSCRIPTOME;
D O I：
10.1007/s11426-023-1793-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Single-cell multi-omics technologies have thrived in recent years. The combined studies of different modalities in single cells have enabled comprehensive insights into the complex functional networks of vital biomacromolecules, thus paving the way for a thorough understanding of cell biology and pathology. In this review, we focus on the advances of single-cell multi-omics technologies utilizing sequencing strategies and propose potential perspectives.
引用
收藏
页码：3024 / 3043
页数：20
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