Inotuzumab Ozogamicin plus Blinatumumab plus /- Rituximab plus Mini-Hcvd Shows Improved Tolerability with Similar Efficacy Compared to E1910 in Treatment of Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia in Older Adults

被引：0

作者：

Scott, Jordan ^{[1
]}

Poblete, Samantha ^{[1
]}

Vega, Jared ^{[1
]}

Przespolewski, Amanda C. ^{[2
]}

Thompson, James E.

Griffiths, Elizabeth A. ^{[3
]}

Sung, Pamela Jeannette ^{[3
]}

Green, Steven ^{[1
]}

Yu, Han ^{[4
]}

Shenal, Michael ^{[5
]}

Przespolewski, Eugene ^{[1
]}

Wang, Eunice S. ^{[2
]}

Baron, Jeffrey ^{[1
]}

机构：

[1] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[2] Roswell Pk Comprehens Canc Ctr, Dept Med, Buffalo, NY USA

[3] Roswell Pk Comprehens Canc Ctr, Dept Med, Leukemia Serv, Buffalo, NY USA

[4] Roswell Pk Canc Inst, Buffalo, NY USA

[5] Univ Buffalo, Sch Pharm & Pharmaceut Sci, Buffalo, NY USA

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-181332

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4

共 19 条

[1] Updated results from a phase II study of mini-hyper-CVD (mini-HCVD) plus inotuzumab ozogamicin (INO), with or without blinatumomab (Blina), in older adults with newly diagnosed Philadelphia chromosome (Ph)-negative B-cell acute lymphoblastic leukemia (ALL).
Macaron, Walid
Kantarjian, Hagop M.
Short, Nicholas James
Ravandi, Farhad
Jain, Nitin
Kadia, Tapan M.
Haddad, Fadi
Valero, Yesid Alvarado
Daver, Naval Guastad
Borthakur, Gautam
Dinardo, Courtney Denton
Konopleva, Marina
Wierda, William G.
Jacob, Jovitta
Roy, Edith
Loiselle, Christopher
Milton, Anna
Rivera, Juan
Garris, Rebecca
Jabbour, Elias
JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
[2] Efficacy of Inotuzumab Ozogamicin plus Ponatinib Followed by Allogeneic Stem Cell Transplantation in a Patient with Relapsed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Micheva, Ilina
Gerov, Vladimir
Dimitrova, Stela
Efraim, Merlin
CASE REPORTS IN HEMATOLOGY, 2021, 2021
[3] Inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-HCVD) with or without blinatumomab versus standard intensive chemotherapy (HCVAD) as frontline therapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propensity score analysis
Jabbour, Elias J.
Sasaki, Koji
Ravandi, Farhad
Short, Nicholas J.
Garcia-Manero, Guillermo
Daver, Naval
Kadia, Tapan
Konopleva, Marina
Jain, Nitin
Cortes, Jorge
Issa, Ghayas C.
Jacob, Jovitta
Kwari, Monica
Thompson, Philip
Garris, Rebecca
Pemmaraju, Naveen
Yilmaz, Musa
O'Brien, Susan M.
Kantarjian, Hagop M.
CANCER, 2019, 125 (15) : 2579 - 2586
[4] Low-intensity chemotherapy (mini-HCVD) and ponatinib followed by blinatumomab (blina) and ponatinib for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph plus ALL): A phase II study
Nasr, Lewis Fady
Jabbour, Elias
Haddad, Fadi
Short, Nicholas James
Macaron, Walid
Nasnas, Cedric Christophe
Zoghbi, Marianne
Issa, Ghayas C.
Yilmaz, Musa
Daver, Naval Guastad
Pemmaraju, Naveen
Masarova, Lucia
Ravandi, Farhad
Jain, Nitin
Deen, Wuliamatu
Loiselle, Christopher
Waller, Lourdes
Banks, Glenda
Garris, Rebecca
Kantarjian, Hagop M.
JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
[5] Updated Results from a Phase II Study of Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia
Short, Nicholas J.
Kantarjian, Hagop
Ravandi, Farhad
Huang, Xuelin
Jain, Nitin
Kadia, Tapan M.
Khoury, Joseph D.
Jorgensen, Jeffrey L.
Wang, Sa A.
Alvarado, Yesid
Burger, Jan A.
Daver, Naval
Borthakur, Gautam
DiNardo, Courtney D.
Konopleva, Marina
Pemmaraju, Naveen
Garcia-Manero, Guillermo
Wierda, William G.
Kornblau, Steven M.
Jacob, Jovitta
Kwari, Monica
Rausch, Caitlin R.
Loiselle, Christopher
Milton, Anna
Rivera, Juan
Garris, Rebecca
O'Brien, Susan M.
Jabbour, Elias J.
BLOOD, 2021, 138
[6] Reduced-Intensity Chemotherapy with Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: Results from a Phase II Study
Short, Nicholas J.
Kantarjian, Hagop M.
Ravandi, Farhad
Huang, Xuelin
Jain, Nitin
Kadia, Tapan M.
Khoury, Joseph D.
Jorgensen, Jeffrey L.
Wang, Sa A.
Alvarado, Yesid
Burger, Jan A.
Daver, Naval
Borthakur, Gautam
DiNardo, Courtney D.
Konopleva, Marina
Pemmaraju, Naveen
Garcia-Manero, Guillermo
Wierda, William G.
Kornblau, Steven M.
Jacob, Jovitta
Rostykus, Meagan
Kwari, Monica
Rausch, Caitlin R.
Loiselle, Christopher
Milton, Anna
Rivera, Juan
Garris, Rebecca
O'Brien, Susan M.
Jabbour, Elias
BLOOD, 2020, 136
[7] A Phase II Study of Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia: Updated Results and Predictors for Outcomes
Nasnas, Patrice
Jabbour, Elias
Short, Nicholas
Ravandi, Farhad
Huang, Xuelin
Jain, Nitin
Kadia, Tapan M.
Alvarado, Yesid
Burger, Jan A.
Daver, Naval
Borthakur, Gautam
DiNardo, Courtney D.
Konopleva, Marina
Garcia-Manero, Guillermo
Wierda, William G.
Jacob, Jovitta
Deen, Wuliamatu
Kwari, Monica
Loiselle, Christopher
Roy, Edith
Milton, Anna
Rivera, Juan
Garris, Rebecca
Kantarjian, Hagop
BLOOD, 2022, 140 : 11679 - 11682
[8] A Prognostic Model for Survival in Patients with Relapsed/Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia on the Combination of Low-Intensity Chemotherapy Plus Inotuzumab Ozogamicin with or without Blinatumomab
Sasaki, Koji
Kantarjian, Hagop M.
Ravandi, Farhad
Short, Nicholas J.
Kebriaei, Partow
Huang, Xuelin
Jain, Nitin
Konopleva, Marina
Garcia-Manero, Guillermo
Champlin, Richard E.
Kadia, Tapan M.
Takahashi, Koichi
Rafei, Hind
Wang, Sa A.
Khoury, Joseph D.
Jorgensen, Jeffrey L.
Khouri, Maria
Jacob, Jovitta
Garris, Rebecca
O'Brien, Susan M.
Jabbour, Elias
BLOOD, 2020, 136
[9] Hyper-CVAD plus ofatumumab versus hyper-CVAD plus rituximab as frontline therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propensity score analysis
Sasaki, Koji
Kantarjian, Hagop M.
Morita, Kiyomi
Short, Nicholas J.
Konopleva, Marina
Jain, Nitin
Ravandi, Farhad
Garcia-Manero, Guillermo
Wang, Sa
Khoury, Joseph D.
Jorgensen, Jeffrey L.
Champlin, Richard E.
Khouri, Issa F.
Kebriaei, Partow
Schroeder, Heather M.
Khouri, Maria
Garris, Rebecca
Takahashi, Koichi
O'Brien, Susan M.
Jabbour, Elias J.
CANCER, 2021, 127 (18) : 3381 - 3389
[10] Phase 2 Trial of Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Patients with Newly Diagnosed Philadelphia ChromosomeNegative B-Cell Acute Lymphoblastic Leukemia
Jen, lWei-Ying
Jabbour, Elias
Haddad, Fadi G.
Short, Nicholas J.
Jain, Nitin
Kadia, Tapan M.
Daver, Naval
Borthakur, Gautam
Nasr, Lewis
DiNardo, Courtney D.
Zoghbi, Marianne
Jacob, Jovitta
Roy, Edith
Loiselle, Christopher
Milton, Anna
Rivera, Juan
Garris, Rebecca
Ravandi, Farhad
Kantarjian, Hagop M.
BLOOD, 2023, 142

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