Two New Pairs of Enantiomeric Butenolides from the Marine Sponge Suberties sp.

被引：0
|
作者：
Li, Dai-Chun [1 ]
Liang, Hui-Xian [1 ]
Liao, Xiao-Jian [1 ]
Xing, Xi-Wen [1 ]
Xu, Shi-Hai [1 ]
Zhao, Bing-Xin [1 ]
机构：
[1] Jinan Univ, Coll Chem & Mat Sci, Dept Chem, Guangzhou 510632, Peoples R China
来源：
CHEMISTRY & BIODIVERSITY | 2023年 / 20卷 / 08期
基金：
中国国家自然科学基金;
关键词：
anti-inflammatory activity; butenolides; enantiomer; marine sponge; Suberties; HETEROAROMATIC ALKALOIDS; SUBERITES; SESTERTERPENES; NAKIJINAMINES; DERIVATIVES; DITERPENES;
D O I：
10.1002/cbdv.202300950
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new pairs of enantiomeric butenolides, (+)- and (-)-suberiteslide A, (+)- and (-)-subertieslide B had been obtained from the marine sponge Suberties sp. The structures with absolute configurations of these compounds were unequivocally determined by spectroscopic analyses and ECD (Electronic Circular Dichroism) method. It was the first separation of butenolides from the marine sponges of genus Suberites. Additionally, the anti-inflammatory, antibacterial and cytotoxic activities of these compounds were evaluated. The result indicated that only (-)-subertieslide B showed weak anti-inflammatory activity with the IC50 value of 40.8 & mu;M.
引用
收藏
页数：4
相关论文
共 50 条
  • [1] Two new alkaloids from marine sponge Callyspongia sp.
    Yang, Bin
    Tao, Huaming
    Zhou, Xuefeng
    Lin, Xiu-Ping
    Liu, Yonghong
    [J]. NATURAL PRODUCT RESEARCH, 2013, 27 (4-5) : 433 - 437
  • [2] Two new diketopiperazines from the marine sponge Dysidea sp.
    Lei, Yu
    Liao, Xiao-Jian
    Xing, Xi-Wen
    Xu, Shi-Hai
    Zhao, Bing-Xin
    [J]. NATURAL PRODUCT RESEARCH, 2024,
  • [3] (+)- and (-)-Tedanine, a pair of new enantiomeric indolone alkaloids from the marine sponge Tedania sp.
    Guo, Ze-Jie
    Liang, Hui-Xian
    Lian, Xiao-Ying
    Liao, Xiao-Jian
    Xing, Xi-Wen
    Xu, Shi-Hai
    Zhao, Bing-Xin
    [J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023,
  • [4] (+)- and (-)-Tedanine, a pair of new enantiomeric indolone alkaloids from the marine sponge Tedania sp.
    Guo, Ze-Jie
    Liang, Hui-Xian
    Lian, Xiao-Ying
    Liao, Xiao-Jian
    Xing, Xi-Wen
    Xu, Shi-Hai
    Zhao, Bing-Xin
    [J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023, : 328 - 333
  • [5] Cacolides: Sesterterpene Butenolides from a Southern Australian Marine Sponge, Cacospongia sp.
    Khushi, Shamsunnahar
    Nahar, Laizuman
    Salim, Angela A.
    Capon, Robert J.
    [J]. MARINE DRUGS, 2018, 16 (11):
  • [6] Two new bromotyrosine derivatives from the marine sponge Pseudoceratina sp.
    Ma, Ke
    Yang, Yi
    Deng, Zhiwei
    de Voogd, Nicole J.
    Proksch, Peter
    Lin, Wenhan
    [J]. CHEMISTRY & BIODIVERSITY, 2008, 5 (07) : 1313 - 1320
  • [7] Two New Thyminenol Derivatives from the Marine Sponge Haliclona sp.
    Wang, Bin
    Lin, Yaocai
    Chen, Yinning
    Huang, Riming
    [J]. NATURAL PRODUCT COMMUNICATIONS, 2014, 9 (04) : 471 - 472
  • [8] TWO NEW PHTHALATE DERIVATIVES FROM THE MARINE SPONGE Haliclona sp.
    Wang, Bin
    Zhou, Heying
    Gao, Chenghai
    Huang, Riming
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2018, 54 (04) : 726 - 728
  • [9] Two New Phthalate Derivatives from the Marine Sponge Haliclona sp.
    Bin Wang
    Heying Zhou
    Chenghai Gao
    Riming Huang
    [J]. Chemistry of Natural Compounds, 2018, 54 : 726 - 728
  • [10] (-)-Wistarin from the marine sponge Ircinia sp.:: the first case of enantiomeric sesterterpenes
    Fontana, A
    Fakhr, I
    Mollo, E
    Cimino, G
    [J]. TETRAHEDRON-ASYMMETRY, 1999, 10 (20) : 3869 - 3872
12345