Genomic and Single Cell Transcriptomic Analyses in Autism Spectrum Disorder

被引：0
|
作者：
Li, Yijing [1 ]
Huang, Raven [2 ]
机构：
[1] Webb Sch, Claremont, CA 91711 USA
[2] East China Normal Univ, Shanghai, Peoples R China
来源：
2023 13TH INTERNATIONAL CONFERENCE ON BIOSCIENCE, BIOCHEMISTRY AND BIOINFORMATICS, ICBBB 2023 | 2023年
关键词：
Autism spectrum disorder; Genomic sequencing; stress-response; prenatal stress; OXIDATIVE STRESS; DEFECTS; OBESITY; STATES;
D O I：
10.1145/3586139.3586146
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Autism Spectrum Disorder (ASD) is a neurological developmental disorder characterized by repetitive behaviors accompanied by communication and social interaction impairment.In this paper, the effect of prenatal stress factors on ASD was investigated by collecting single-cell RNA sequencing and calculation. The results suggest that stress responses, such as obesity-related stress and oxidative stress, may be related to neuronal death and contribute to the development of ASD. In addition, studies have shown that stress response genes decline over time under low temperature conditions.
引用
收藏
页码：47 / 58
页数：12
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