PARTIAL MYELOID INHIBITION OF KEY GLYCOLYTIC ENZYME PFKFB3 INCREASES HEPATIC STEATOSIS AND INFLAMMATION, BUT DOES NOT AFFECT ATHEROSCLEROSIS

被引：0

作者：

Tillie, R. ^{[1
]}

De Bruijn, J. ^{[1
]}

Dobie, R. ^{[2
]}

Perales-Paton, J. ^{[3
]}

Van Kuijk, K. ^{[1
]}

Gijbels, M. ^{[1
]}

Temmerman, L. ^{[1
]}

Ghosheh, Y. ^{[4
]}

Goossens, G. ^{[5
]}

Carmeliet, P. ^{[6
]}

Ley, K. ^{[4
]}

Henderson, N. ^{[2
]}

Saez-Rodriguez, J. ^{[3
]}

Wouters, K. ^{[7
]}

Sluimer, J. ^{[1
]}

机构：

[1] Maastricht Univ, Pathol, Med Ctr, Maastricht, Netherlands

[2] Univ Edinburgh, Mrc Ctr Inflammat Res, Edinburgh, Midlothian, Scotland

[3] Heidelberg Univ, Inst Computat Biomed, Heidelberg, Germany

[4] La Jolla Inst Immunol, Ctr Autoimmun & Inflammat, San Diego, CA USA

[5] Maastricht Univ, Human Biol, Maastricht, Netherlands

[6] Katholieke Univ Leuven, Lab Angiogenesis & Vasc Metab, Leuven, Belgium

[7] Maastricht Univ, Internal Med, Maastricht, Netherlands

来源：

ATHEROSCLEROSIS | 2023年 / 379卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

O079

引用

页数：2

共 11 条

[1] Inhibition of the Key Glycolytic Enzyme PFKFB3 with Novel Compounds Suppresses Angiogenesis
Abdali, Anahita
Corsini, Alberto
Baci, Denisa
De Dominicis, Carlo
Zanda, Matteo
Gelmi, Maria Luisa
Bellosta, Stefano
[J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018, 38
[2] ANGIOGENESIS INHIBITION WITH NOVEL COMPOUNDS TARGETING THE KEY GLYCOLYTIC ENZYME PFKFB3
Abdali, A.
Corsini, A.
Baci, D.
De Dominicis, C.
Zanda, M.
Gelmi, M. L.
Bellosta, S.
[J]. ATHEROSCLEROSIS, 2018, 275 : E127 - E127
[3] Inhibition of the Key Glycolytic Enzyme PFKFB3 with Novel Compounds Suppresses Angiogenesis
Abdali, Anahita
Corsini, Alberto
Baci, Denisa
De Dominicis, Carlo
Zanda, Matteo
Gelmi, Maria Luisa
Bellosta, Stefano
[J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018, 38
[4] In vitro angiogenesis inhibition with selective compounds targeting the key glycolytic enzyme PFKFB3
Abdali, Anahita
Baci, Denisa
Damiani, Isabella
Belloni, Federica
De Dominicis, Carlo
Gelmi, Maria Luisa
Corsini, Alberto
Bellosta, Stefano
[J]. PHARMACOLOGICAL RESEARCH, 2021, 168
[5] Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis
Tillie, Renee J. H. A.
De Bruijn, Jenny
Perales-Paton, Javier
Temmerman, Lieve
Ghosheh, Yanal
Van Kuijk, Kim
Gijbels, Marion J.
Carmeliet, Peter
Ley, Klaus
Saez-Rodriguez, Julio
Sluimer, Judith C.
[J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
[6] Partial Inhibition of the Key Glycolytic Enzyme PFKFB3 in Myeloid Cells Impacts Whole-Body Immune Cell and Liver Metabolism, But Not Atherogenesis
de Bruijn, Jenny
van Kuijk, Kim
Bijnen, Mitchell
Sander, Bianca
Gijbels, Marion
Carmeliet, Peter
Wouters, Kristiaan
Sluimer, Judith C.
[J]. JOURNAL OF VASCULAR RESEARCH, 2019, 56 : 24 - 24
[7] Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis
Tillie, Renee J. H. A.
De Bruijn, Jenny
Perales-Paton, Javier
Temmerman, Lieve
Ghosheh, Yanal
Van Kuijk, Kim
Gijbels, Marion J.
Carmeliet, Peter
Ley, Klaus
Saez-Rodriguez, Julio
Sluimer, Judith C.
[J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
[8] PARTIAL INHIBITION OF THE KEY GLYCOLYTIC ENZYME PFKFB3 IN MYELOID CELLS IMPACTS WHOLE-BODY IMMUNE CELL AND LIVER METABOLISM, BUT NOT ATHEROGENESIS.
De Bruijn, J.
van Kuijk, K.
Bijnen, M.
Gijbels, M.
Wouters, K.
Carmeliet, P.
Sluimer, J.
[J]. ATHEROSCLEROSIS, 2019, 287 : E19 - E20
[9] Disruption of Myeloid Cell-Specific PFKFB3 Exacerbates Diet-Induced Hepatic Steatosis and Inflammation in Mice
Li, Honggui
Ma, Linqiang
Zhou, Jing
Luo, Xianjun
Francis, Heather L.
Glaser, Shannon
Meng, Fanyin
Alpini, Gianfranco
Wu, Chaodong
[J]. HEPATOLOGY, 2018, 68 : 732A - 732A
[10] Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3)
Brooke, Darby G.
van Dam, Ellen M.
Watts, Colin K. W.
Khoury, Amanda
Dziadek, Marie A.
Brooks, Hilary
Graham, Lisa-Jane K.
Flanagan, Jack U.
Denny, William A.
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (03) : 1029 - 1039

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