A new phenyl 6,7-dihydroxygeranyl ether derivative from a marine-derived fungus strain of Penicillium arabicum ZH3-9

被引：2

作者：

Yang, Jinpeng ^{[1
]}

Zhang, Xinwan ^{[1
]}

Xu, Wei ^{[1
]}

Xu, Xiuli ^{[1
,3
]}

Song, Fuhang ^{[2
]}

机构：

[1] China Univ Geosci, Sch Ocean Sci, Beijing, Peoples R China

[2] Beijing Technol & Business Univ, Sch Light Ind, Beijing, Peoples R China

[3] China Univ Geosci, Sch Ocean Sci, Beijing 100083, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2024年 / 38卷 / 13期

基金：

中国国家自然科学基金;

关键词：

Marine-derived fungus; Penicillium arabicum ZH3-9; Staphylococcus aureus;

D O I：

10.1080/14786419.2023.2169917

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new phenyl 6,7-dihydroxygeranyl ether derivative, named (Z)-4-((6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy)benzoic acid (1), and 8 known compounds (2-9) were characterized from a marine-derived fungus strain of Penicillium arabicum ZH3-9 isolated from a mud sample collected from the coast of Zhuhai, Guangdong Province, China. The structure of 1 was elucidated by HRESIMS, 1 D and 2 D NMR. All compounds were evaluated antimicrobial activities against Candida albicans, Staphylococcus aureus, and Escherichia coli. Compounds 4-6 displayed antibacterial activity against S. aureus with minimum inhibitory concentrations of 50, 12.5, and 50 mu g/mL.

引用

页码：2231 / 2236

页数：6

共 9 条

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不详
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