Midkine Dependent Immunosuppressive Environment in Cerebrospinal Fluid May Promote Leptomeningeal Metastases of EGFR mutant NSCLC

被引:0
|
作者
Li, Y. -S. [1 ]
Yin, K. [1 ]
Lai, W. -P. [2 ]
Zheng, M. -M. [1 ]
Tu, H. -Y. [1 ]
Wang, Z. [1 ]
Zeng, L. [1 ]
Jiang, B. -Y. [1 ]
Yang, J. -J. [1 ]
Zhou, Q. [1 ]
Zhong, W. -Z. [1 ]
Yang, X. -N. [1 ]
Chen, H. -J. [1 ]
Wu, Y. -L. [1 ]
机构
[1] Southern Med Univ, Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Guangdong Lung Canc Inst,Guangdong Prov Key Lab, Guangzhou, Peoples R China
[2] Jinan Univ, Inst Hematol, Sch Med, Guangzhou, Peoples R China
关键词
Leptomeningeal metastases; immunosuppressive environment; midkine;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P1.09-02
引用
收藏
页码:S199 / S200
页数:2
相关论文
共 38 条
  • [1] Unique Genetic Profiles from Cerebrospinal Fluid Could Predict Survival of EGFR-Mutant NSCLC with Leptomeningeal Metastases
    Li, Y.
    Jiang, B.
    Zheng, M.
    Tu, H.
    Yang, J.
    Zhang, X.
    Ye, J.
    Zhou, Q.
    Zhong, W.
    Zhang, C.
    Chuai, S.
    Wu, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S482 - S482
  • [2] Unique Genetic Profiles from Circulating Cell-Free DNA of Cerebrospinal Fluid in Leptomeningeal Metastases of EGFR Mutant NSCLC
    Jiang, B.
    Li, Y.
    Yang, J. -
    Yang, X.
    Zhou, Q.
    Zhong, W.
    Zhang, X.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1771 - S1771
  • [3] Genotyping of Cerebrospinal Fluid Associated With Osimertinib Response and Resistance for Leptomeningeal Metastases in EGFR-Mutated NSCLC
    Zheng, Mei-Mei
    Li, Yang-Si
    Tu, Hai-Yan
    Jiang, Ben-Yuan
    Yang, Jin-Ji
    Zhou, Qing
    Xu, Chong-Rui
    Yang, Xiao-Rong
    Wu, Yi-Long
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (02) : 250 - 258
  • [4] ORA-LM: Molecular Analysis in Cerebrospinal Fluid of ALK or EGFR Positive NSCLC Patients with Leptomeningeal Metastases
    van der Wel, T.
    Boelens, M. C.
    Jebbink, M.
    Smulders, S. A.
    Tiemessen, M. A.
    Maas, K. W.
    Luitse, M. J.
    Compter, A.
    Boltjes, R. P. B.
    Sol, N.
    Monkhorst, K.
    van den Broek, D.
    Smit, E. F.
    de langen, A. J.
    Brandsma, D.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (11) : S354 - S355
  • [5] Osimertinib Improves overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastases
    Ye, Qiuyue
    Xu, Yan
    Zhao, Jing
    Gao, Xiaoxing
    Chen, Minjiang
    Pan, Ruili
    Zhong, Wei
    Wang, Mengzhao
    TRANSLATIONAL ONCOLOGY, 2023, 31
  • [6] EGFR mutation status of paired cerebrospinal fluid and plasma samples in EGFR mutant non-small cell lung cancer with leptomeningeal metastases
    Jing Zhao
    Xin Ye
    Yan Xu
    Minjiang Chen
    Wei Zhong
    Yun Sun
    Zhenfan Yang
    Guanshan Zhu
    Yi Gu
    Mengzhao Wang
    Cancer Chemotherapy and Pharmacology, 2016, 78 : 1305 - 1310
  • [7] EGFR mutation status of paired cerebrospinal fluid and plasma samples in EGFR mutant non-small cell lung cancer with leptomeningeal metastases
    Zhao, Jing
    Ye, Xin
    Xu, Yan
    Chen, Minjiang
    Zhong, Wei
    Sun, Yun
    Yang, Zhenfan
    Zhu, Guanshan
    Gu, Yi
    Wang, Mengzhao
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 78 (06) : 1305 - 1310
  • [8] Osimertinib Leads the Way Toward Improving Outcomes of EGFR-Mutant NSCLC With Leptomeningeal Metastases
    Zheng, Mei-Mei
    Li, Yang-Si
    Sun, Hao
    Wu, Yi-Long
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (02) : E12 - E14
  • [9] Circulating Cell-Free DNA of Cerebrospinal Fluid May Function as Liquid Biopsy for Leptomeningeal Metastases of ALK Rearrangement NSCLC
    Li, Y.
    Jiang, B.
    Yang, J. -.
    Zhang, X.
    Zhang, Z.
    Zhou, Q.
    Tu, H.
    Wang, Z.
    Chen, H.
    Xu, C.
    Wang, B.
    Wu, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1739 - S1739
  • [10] Genetic profiling of cell-free DNA from cerebrospinal fluid: opening the barrier to leptomeningeal metastasis in EGFR-mutant NSCLC
    Vanden Bempt, I.
    Wauters, E.
    Vansteenkiste, J.
    ANNALS OF ONCOLOGY, 2018, 29 (04) : 789 - 791