Double insertions of SMEFT operators in gluon fusion Higgs boson production

被引:8
|
作者
Vedi, Mahima [1 ]
Smith, Jennifer R. [1 ]
Hayman, G. Thomas [1 ]
Tutaj, Monika [1 ]
Brodie, Kent C. [2 ]
De Pons, Jeffrey L. [1 ]
Demos, Wendy M. [1 ]
Gibson, Adam C. [1 ]
Kaldunski, Mary L. [1 ]
Lamers, Logan [1 ]
Laulederkind, Stanley J. F. [1 ]
Thota, Jyothi [1 ]
Thorat, Ketaki [1 ]
Tutaj, Marek A. [1 ]
Wang, Shur-Jen [1 ]
Zacher, Stacy [3 ]
Dwinell, Melinda R. [1 ]
Kwitek, Anne E. [1 ,4 ]
机构
[1] Med Coll Wisconsin, Rat Genome Database, Dept Physiol, B5235 BSB,8701 Watertown Plank Rd, Milwaukee, WI 53226 USA
[2] Med Coll Wisconsin, Clin & Translat Sci Inst, Milwaukee, WI 53226 USA
[3] Med Coll Wisconsin, Finance & Adm, Milwaukee, WI 53226 USA
[4] Med Coll Wisconsin, Dept Biomed Engn, Milwaukee, WI 53226 USA
基金
美国国家卫生研究院;
关键词
Rattus norvegicus; Rat Genome Database; genomics; quantitative phenotype; FAIR data; rat genetics; rat strain; comparative genome; RAT GENOME; DATABASE; GENE; MODEL; IMPROVEMENTS; EXPRESSION; SEQUENCE;
D O I
10.1093/genetics/iyad042
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The Rat Genome Database (RGD, ) has evolved from simply a resource for rat genetic markers, maps, and genes, by adding multiple genomic data types and extensive disease and phenotype annotations and developing tools to effectively mine, analyze, and visualize the available data, to empower investigators in their hypothesis-driven research. Leveraging its robust and flexible infrastructure, RGD has added data for human and eight other model organisms (mouse, 13-lined ground squirrel, chinchilla, naked mole-rat, dog, pig, African green monkey/vervet, and bonobo) besides rat to enhance its translational aspect. This article presents an overview of the database with the most recent additions to RGD's genome, variant, and quantitative phenotype data. We also briefly introduce Virtual Comparative Map (VCMap), an updated tool that explores synteny between species as an improvement to RGD's suite of tools, followed by a discussion regarding the refinements to the existing PhenoMiner tool that assists researchers in finding and comparing quantitative data across rat strains. Collectively, RGD focuses on providing a continuously improving, consistent, and high-quality data resource for researchers while advancing data reproducibility and fulfilling Findable, Accessible, Interoperable, and Reusable (FAIR) data principles.
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页数:15
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