Factors associated with household transmission of SARS-CoV-2 omicron variant to health care workers: A retrospective cohort study

被引:0
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作者
Kagami, Keisuke [1 ,2 ]
Oyamada, Reiko [1 ]
Watanabe, Tsubasa [1 ]
Nakakubo, Sho [1 ,3 ]
Hayashi, Takahiro [1 ]
Iwasaki, Sumio [1 ,4 ]
Fukumoto, Tatsuya [1 ,4 ]
Usami, Takayuki [1 ,4 ]
Hayasaka, Kasumi [1 ,4 ]
Fujisawa, Shinichi [4 ]
Watanabe, Chiaki [4 ]
Nishida, Mutsumi [4 ]
Teshima, Takanori [4 ,5 ]
Niinuma, Yusuke [1 ,2 ]
Yokota, Isao [6 ]
Takekuma, Yoh [2 ]
Sugawara, Mitsuru [2 ,7 ]
Ishiguro, Nobuhisa [1 ]
机构
[1] Hokkaido Univ Hosp, Dept Infect Control & Prevent, Kita 14 Jo,Nishi 5 Chome,Kita Ku, Sapporo, Hokkaido 0608648, Japan
[2] Hokkaido Univ Hosp, Dept Pharm, Sapporo, Hokkaido, Japan
[3] Hokkaido Univ, Fac Med, Dept Resp Med, Sapporo, Hokkaido, Japan
[4] Hokkaido Univ Hosp, Div Lab & Transfus Med, Sapporo, Hokkaido, Japan
[5] Hokkaido Univ, Fac Med, Dept Hematol, Sapporo, Hokkaido, Japan
[6] Hokkaido Univ, Grad Sch Med, Dept Biostat, Sapporo, Hokkaido, Japan
[7] Hokkaido Univ, Fac Pharmaceut Sci, Lab Pharmacokinet, Sapporo, Hokkaido, Japan
关键词
household transmission; nursing; omicron variant; SARS-CoV-2; vaccine;
D O I
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中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
Aim: The aim of this study was to determine the risk factors for household transmission of the omicron variant of SARS-CoV-2.Background: The household infection rate has been reported to be higher for the omicron variant than for non-omicron variants of SARS-CoV-2. Determination of the risk factors for household transmission of the omicron variant is therefore important.Design: A Retrospective Cohort Study was conducted.Methods: When family members of health care workers (HCWs) were found to be infected with SARS-CoV-2, the HCWs had to receive two nucleic acid amplification tests for SARS-CoV-2: immediately after and 5 to 10 days after the onset of COVID-19 in the family members. Risk factors of household transmission were analysed by comparing cases (HCWs infected with SARS-CoV-2) and controls (HCWs not infected with SARS-CoV-2) using multivariable analysis.Results: Unvaccinated status (OR: 3.97), age of index cases (<= 6 years) (OR: 1.94) and staying at home with index cases (OR: 10.18) were risk factors for household transmission.Conclusion: If there is a strong desire to avoid household infection, family members infected with SARS-CoV-2 should live separately during the period of viral shedding.
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页数:6
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