Multifunctional role of nanoparticles for the diagnosis and therapeutics of cardiovascular diseases

被引:6
|
作者
Arshad, Ihtesham [1 ]
Kanwal, Ayesha [1 ]
Zafar, Imran [2 ]
Unar, Ahsanullah [3 ]
Mouada, Hanane [4 ]
Razia, Iashia Tur [11 ]
Arif, Safina [5 ]
Ahsan, Muhammad [6 ]
Kamal, Mohammad Amjad [7 ,8 ,9 ,10 ,11 ]
Rashid, Summya [12 ]
Khan, Khalid Ali [13 ,14 ]
Sharma, Rohit [15 ]
机构
[1] Univ Okara, Fac Life Sci, Dept Biotechnol, Okara 56300, Pakistan
[2] Virtual Univ, Dept Bioinformat & Computat Biol, Lahore 54700, Punjab, Pakistan
[3] Univ Campania 'L Vanvitelli, Dept Precis Med, Naples, Italy
[4] Inst Sci Univ Ctr Tipaza, Dept Proc Engn, Inst Sci, Tipasa, Algeria
[5] Univ Lahore, Med Lab Technol, Lahore 54590, Pakistan
[6] Univ Okara, Inst Environm & Agr Sci, Dept Environm Sci, Okara 56300, Pakistan
[7] Sichuan Univ, West China Hosp, Inst Syst Genet, Frontiers Sci Ctr Dis, Chengdu, Peoples R China
[8] King Abdulaziz Univ, King Fahd Med Res Ctr, Riyadh, Saudi Arabia
[9] Daffodil Int Univ, Fac Allied Hlth Sci, Dept Pharm, Birulia, Bangladesh
[10] Enzymoics, 7 Peterlee Pl, Hebersham, NSW 2770, Australia
[11] Novel Global Community Educ Fdn, Hebersham, Australia
[12] Prince Sattam BinAbdulaziz Univ, Coll Pharm, Dept Pharmacol & Toxicol, POB 173, Al Kharj 11942, Saudi Arabia
[13] King Khalid Univ, Res Ctr Adv Mat Sci RCAMS, Unit Bee Res & Honey Prod, POB 9004, Abha 61413, Saudi Arabia
[14] King Khalid Univ, Appl Coll, POB 9004, Abha 61413, Saudi Arabia
[15] Banaras Hindu Univ, Inst Med Sci, Fac Ayurveda, Dept Rasa Shastra & Bhaishajya Kalpana, Varanasi 221005, Uttar Pradesh, India
关键词
Cardiovascular diseases; Nano-cardiovascular; Nanomedicine; Nanoscience; Nano-drug delivery system; NPs; DRUG-DELIVERY; IN-VITRO; LIPID NANOPARTICLES; GOLD NANOPARTICLES; CONTRAST AGENTS; GREEN SYNTHESIS; THERAPY; NANOTECHNOLOGY; SURFACE; SYSTEM;
D O I
10.1016/j.envres.2023.117795
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The increasing burden of cardiovascular disease (CVD) remains responsible for morbidity and mortality worldwide; their effective diagnostic or treatment methods are of great interest to researchers. The use of NPs and nanocarriers in cardiology has drawn much interest. The present comprehensive review provides deep in-sights into the use of current and innovative approaches in CVD diagnostics to offer practical ways to utilize nanotechnological interventions and the critical elements in the CVD diagnosis, associated risk factors, and management strategies of patients with chronic CVDs. We proposed a decision tree-based solution by discussing the emerging applications of NPs for the higher number of rules to increase efficiency in treating CVDs. This review-based study explores the screening methods, tests, and toxicity to provide a unique way of creating a multi-parametric feature that includes cutting-edge techniques for identifying cardiovascular problems and their treatments. We discussed the benefits and drawbacks of various NPs in the context of cost, space, time and complexity that have been previously suggested in the literature for the diagnosis of CVDs risk factors. Also, we highlighted the advances in using NPs for targeted and improved drug delivery and discussed the evolution toward the nano-cardiovascular potential for medical science. Finally, we also examined the mixed-based diagnostic approaches crucial for treating cardiovascular disorders, broad applications and the potential future applications of nanotechnology in medical sciences.
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页数:17
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