A study on the fabrication of metal microneedle array electrodes for ECG detection based on low melting point Bi-In-Sn alloys

被引:2
|
作者
Gwak, Hyunjong [1 ]
Cho, Sungbo [2 ]
Song, Yoon-Jae [3 ]
Park, Jung-Hwan [1 ]
Seo, Soonmin [1 ]
机构
[1] Gachon Univ, Dept BioNano Technol, Seongnam Si 13120, Gyeonggi Do, South Korea
[2] Gachon Univ, Dept Elect Engn, Seongnam Si 13120, Gyeonggi Do, South Korea
[3] Gachon Univ, Dept Life Sci, Seongnam Si 13120, Gyeonggi Do, South Korea
基金
新加坡国家研究基金会;
关键词
DRY ELECTRODES; PERMEATION;
D O I
10.1038/s41598-023-50472-y
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study describes the fabrication and characteristics of microneedle array electrodes (MAEs) using Bismuth-Indium-Tin (Bi-In-Sn) alloys. The MAEs consist of 57 pyramid-shaped needles measuring 340 mu m wide and 800 mu m high. The fabrication process involved micromolding the alloys in a vacuum environment. Physical tests demonstrated that Bi-In-Sn MAEs have good mechanical strength, indicating their suitability for successful skin penetration. The electrode-skin interface impedance test confirmed that Bi-In-Sn MAEs successfully penetrated the skin. Impedance measurements revealed the importance of insulating the microneedle electrodes for optimal electrical performance, and a UV-curable Polyurethane Acrylate coating was applied to enhance insulation. Electrocardiogram measurements using the Bi-In-Sn MAEs demonstrated performance comparable to that of traditional Ag/AgCl electrodes, which shows promise for accurate data collection. Overall, the study demonstrates successful, minimally-invasive skin insertion, improved electrical insulation, and potential applications of Bi-In-Sn microneedle array. These findings contribute to advancements in microneedle technology for biomedical applications.
引用
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页数:9
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