Magnetic Particle Imaging-Guided Hyperthermia for Precise Treatment of Cancer: Review, Challenges, and Prospects

被引:10
|
作者
Lei, Siao [1 ,2 ,3 ,4 ]
He, Jie [1 ,2 ,3 ,4 ]
Gao, Pengli [1 ,2 ,3 ,4 ]
Wang, Yueqi [4 ]
Hui, Hui [4 ]
An, Yu [1 ,2 ,3 ,4 ]
Tian, Jie [1 ,2 ,3 ,4 ,5 ]
机构
[1] Beihang Univ, Sch Engn Med, Beijing 100191, Peoples R China
[2] Beihang Univ, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China
[3] Beihang Univ, Minist Ind & Informat Technol Peoples Republ Chin, Key Lab Big Data Based Precis Med, Beijing 100191, Peoples R China
[4] Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
[5] Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai 519000, Peoples R China
关键词
Magnetic particle imaging; Magnetic fluid hyperthermia; Cancer; Precise treatment; IRON-OXIDE NANOPARTICLES; INTENSITY FOCUSED ULTRASOUND; PROTON THERAPY; BREAST-CANCER; CLINICAL-APPLICATIONS; HEATING EFFICIENCY; FLUID HYPERTHERMIA; PLATFORM; RESONANCE; SYSTEM;
D O I
10.1007/s11307-023-01856-z
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Magnetic particle imaging (MPI) is a novel quantitative imaging technique using the nonlinear magnetization behavior of magnetic nanoparticles (MNPs) to determine their local concentration. Magnetic fluid hyperthermia (MFH) is a promising non-invasive therapy using the heating effects of MNPs. MPI-MFH is expected to enable real-time MPI guidance, localized MFH, and non-invasive temperature monitoring, which shows great potential for precise treatment of cancer. In this review, we introduce the fundamentals of MPI and MFH and their applications in the treatment of cancer. Also, we discuss the challenges and prospects of MPI-MFH.
引用
收藏
页码:1020 / 1033
页数:14
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