Favorable outcomes in Hispanic recipients receiving simultaneous pancreas kidney transplantation

被引:1
|
作者
Budhiraja, Pooja [1 ,4 ]
Reddy, Kunam S. [2 ]
Heilman, Raymond L. [1 ]
Jadlowiec, Caroline C. [2 ]
Khamash, Hassan [1 ]
Reddy, Swetha [3 ]
Katariya, Nitin [2 ]
Chakkera, Harini A. [1 ]
机构
[1] Mayo Clin Arizona, Div Med, Phoenix, AZ USA
[2] Mayo Clin Arizona, Dept Surg, Phoenix, AZ USA
[3] Mayo Clin Rochester, Dept Med, Rochester, MN USA
[4] Mayo Clin Hosp, Div Nephrol, 5777 E Mayo Blvd, Phoenix, AZ 85054 USA
关键词
graft survival; Hispanic; race; simultaneous pancreas-kidney transplantation; whites; RACIAL-DIFFERENCES; DIABETES-MELLITUS; HEALTH; DISPARITIES; ACCESS; NEPHROPATHY; MORTALITY; ALLOGRAFT;
D O I
10.1111/ctr.15062
中图分类号
R61 [外科手术学];
学科分类号
摘要
The objective of this study was to compare the long-term outcomes of Hispanic versus white recipients who underwent simultaneous pancreas kidney transplantation (SPKT). This single-center study, conducted from 2003 to 2022, had a median follow-up of 7.5 years. The study included 91 Hispanic and 202 white SPKT recipients. The mean age (44 vs. 46 years), percentage of males (67% vs. 58%), and body mass index (BMI) (25.6 vs. 25.3 kg/m(2)) were similar between the Hispanic and white groups. The Hispanic group had more recipients with type 2 diabetes (38%) compared to the white group (5%, p < .001). The duration of dialysis was longer in Hispanics (640 vs. 473 days, p = .02), and fewer patients received preemptive transplants (10% vs. 29%, p < .01) compared to whites. Hospital length of stay, rates of BK Viremia, and acute rejection episodes within 1 year were similar between the groups. The estimated 5-year kidney, pancreas, and patient survival rates were also similar between the groups, 94%, 81%, and 95% in Hispanics, compared to 90%, 79%, and 90% in whites. Increasing age and longer duration of dialysis were risk factors for death. Although Hispanic recipients had a longer duration on dialysis and fewer preemptive transplants, the survival rates were similar to those of white recipients. However, referring providers and many transplant centers continue to overlook pancreas transplants for appropriately selected patients with type 2 diabetes, particularly among minority populations. As a transplant community, it is crucial that we make efforts to comprehend and tackle these obstacles to transplantation.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Favorable Outcomes in Hispanic Recipients Receiving Simultaneous Pancreas Kidney Transplantation
    Budhiraja, P.
    Heilman, R.
    Reddy, K.
    Jadlowiec, C.
    Khamash, H.
    Katariya, N.
    Reddy, S.
    Chakkera, H.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 23 (06) : S1051 - S1051
  • [2] Favorable Outcomes in Older Recipients Receiving Simultaneous Pancreas Kidney Transplantation
    Budhiraja, Pooja
    Heilman, Raymond L.
    Reddy, Kunam S.
    Jadlowiec, Caroline C.
    Khamash, Hassan A.
    Ninan, Jacob
    Reddy, Swetha
    Me, Hay Me
    Misra, Suman
    Katariya, Nitin
    Chakkera, Harini A.
    [J]. TRANSPLANTATION DIRECT, 2022, 8 (12): : E1413
  • [3] Favorable Outcomes in Older Recipients Receiving Simultaneous Kidney Pancreas Transplantation.
    Budhiraja, P.
    Me, H.
    Ninan, J.
    Reddy, S.
    Misra, S. S.
    Heilman, R.
    Khamash, H.
    Reddy, K.
    Jadloweic, C.
    Katariya, N.
    Chakkera, H.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2022, 22 : 849 - 850
  • [4] Outcomes of Simultaneous Pancreas-Kidney Transplantation in Type 2 Diabetic Recipients
    Sampaio, Marcelo Santos
    Kuo, Hung-Tien
    Bunnapradist, Suphamai
    [J]. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 6 (05): : 1198 - 1206
  • [5] Favorable Outcomes in Older Diabetics Receiving a Simultaneous Kidney Pancreas Transplant Compared to Those Receiving a Living Donor Kidney Transplant.
    Budhiraja, P.
    Me, H.
    Ninan, J.
    Reddy, S.
    Misra, S. S.
    Heilman, R.
    Khamash, H.
    Reddy, K.
    Jadloweic, C.
    Katariya, N.
    Chakkera, H.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2022, 22 : 523 - 523
  • [6] Report of Four Simultaneous Pancreas-Kidney Transplants in HIV-Positive Recipients With Favorable Outcomes
    Grossi, P. A.
    Righi, E.
    Dalla Gasperina, D.
    Donati, D.
    Tozzi, M.
    Mangini, M.
    Astuti, N.
    Cuffari, S.
    Castelli, P.
    Carcano, G.
    Dionigi, G.
    Boggi, U.
    Costa, A. Nanni
    Dionigi, R.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2012, 12 (04) : 1039 - 1045
  • [7] Clinical outcomes of simultaneous pancreas-kidney transplantation in elderly type II diabetic recipients
    Yu Cao
    Jie Zhao
    Gang Feng
    Zhen Wang
    Jianghao Wei
    Yang Xu
    Chunbai Mo
    Wenli Song
    [J]. Diabetology & Metabolic Syndrome, 16
  • [8] Clinical outcomes of simultaneous pancreas-kidney transplantation in elderly type II diabetic recipients
    Cao, Yu
    Zhao, Jie
    Feng, Gang
    Wang, Zhen
    Wei, Jianghao
    Xu, Yang
    Mo, Chunbai
    Song, Wenli
    [J]. DIABETOLOGY & METABOLIC SYNDROME, 2024, 16 (01):
  • [9] Outcomes Of Simultaneous Pancreas/kidney Transplantation In Bmi Extremes
    Al-Kurd, A.
    Safwan, M.
    Kim, D.
    Abouljoud, M.
    Nagai, S.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2019, 19 : 1133 - 1133
  • [10] Outcomes of Pregnancy in Simultaneous Pancreas and Kidney (SPK) Transplant Recipients
    Punjala, S.
    Phillips, B. L.
    Chowdhury, P.
    Pile, T.
    Harding, K.
    Callaghan, C. J.
    Nelson-Piercy, C.
    Drage, M.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 : 1159 - 1159