What is the use of nutraceuticals in dentistry? A scoping review

OBJECTIVE: Recently, nutraceu-ticals have been widely explored in many medi-cal fields and their use is also increasing in oral and dental problems. Since the nutraceutical ev-idence landscape in the literature has not been fully elucidated yet, this review aims to examine the effects of commercially available nutraceu-ticals and their potential evidence and applica-tions in dentistry.MATERIALS AND METHODS: A scoping re-view was conducted following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR)" checklist. The electronic search was performed using PubMed/MEDLINE, EM -BASE, the Cochrane Library, and Web of Science on March 2022. The inclusion criteria include hu-mans, clinical trials, randomized controlled tri-als (RCT), reviews, and systematic reviews pub-lished over the last ten years.RESULTS: 18 studies met the eligibility crite-ria. There were 2 RCTs, 11 systematic reviews, and four narrative reviews. In most studies, the clinical indications were oral leucoplakia, peri-odontitis, osseointegration of implants, oral mu-cositis, oral clefts, and oral health. Probiotics, prebiotics, polyunsaturated fatty acids, and vi-tamins A, B, C, D, and E were the most common nutraceuticals used in dentistry.CONCLUSIONS: Nutraceuticals are foods that, according to the literature, may be useful for preventing and treating dental diseases.