IL-4 within the bone marrow: a key driver of lung tumorigenesis

被引:0
|
作者
Tanaka, Yoshimasa [1 ]
机构
[1] Nagasaki Univ, Ctr Med Innovat, 1-7-1 Sakamoto, Nagasaki 8528588, Japan
关键词
bone marrow; IL-4; non-small cell lung cancer; tumorigenesis; tumor microenvironment;
D O I
10.1093/jleuko/qiae033
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Interleukin-4 in bone marrow serves as a driver of lung cancer. Combining interleukin-4 receptor alpha chain blockade with immune checkpoint inhibitors has the potential for a novel superior cancer immunotherapy targeting the tumor microenvironment.
引用
收藏
页码:791 / 793
页数:3
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