Advances in sesquiterpene lactones extraction

被引：2
|
作者：
Bras, Teresa [1 ,2 ]
Neves, Luisa A. [3 ]
Crespo, Joao G. [3 ]
Duarte, Maria F. [1 ,2 ]
机构：
[1] Polytech Inst Beja IPBeja, Alentejo Biotechnol Ctr Agr & Agrofood CEBAL, P-7801908 Beja, Portugal
[2] CEBAL, MED Mediterranean Inst Agr Environm & Dev, CHANGE Global Change & Sustainabil Inst, P-7801908 Beja, Portugal
[3] Univ NOVA Lisboa, NOVA Sch Sci & Technol, Dept Chem, LAQV REQUIMTE, P-2829516 Caparica, Portugal
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2023年 / 158卷
关键词：
Sesquiterpene lactones; Extraction methodology; Extraction solvents; Purification; Biological activity; ARTEMISIA-ANNUA L; SUPERCRITICAL-FLUID EXTRACTION; PRESSURIZED LIQUID EXTRACTION; IN-VITRO; BIOACTIVE COMPOUNDS; BIOLOGICAL-ACTIVITIES; GREEN EXTRACTION; ANTIMICROBIAL ACTIVITY; PHYTOCHEMICAL ANALYSIS; ASSISTED EXTRACTION;
D O I：
10.1016/j.trac.2022.116838
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Sesquiterpene lactones (SL) group, comprises more than 6000 compounds, with high biological potential. Access to SL biological potential could be achieved by solid-liquid extraction, with solvent and extraction process as key factors for a successful extraction. SL research has been mainly focused on compounds identification, with a large range of solvents being applied, not all corresponding to the European Medicines Agency guidelines, using different conventional extraction methodologies. Moreover, there is still a lack of scientific knowledge regarding the extraction solvent and methodology effect upon SL extraction from plants, and its bioactivity, towards final applications. This review aims to provide a perspective regarding the impact of extraction solvents and method-ologies upon SL extraction efficiency, as well as the purification methods applied till date, highlighting the overall impact on final extraction efficiency, underlying pertinent aspects for future economic valorization opportunities, as well research challenges towards industrial applications regarding SL plants extraction. & COPY; 2022 Elsevier B.V. All rights reserved.
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页数：9
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