PSMA PET-directed surgical metastasis-directed therapy in metachronous prostate cancer

被引：0
|
作者：
Ambrosini, Francesca [1 ,2 ]
Koehler, Daniel [3 ]
Ghadban, Tarik [4 ]
Jacobsen, Frank [5 ]
Knipper, Sophie [1 ]
von Amsberg, Gunhild [1 ,6 ]
Steuber, Thomas [1 ,7 ]
Maurer, Tobias [1 ,7 ]
机构：
[1] Univ Hosp Hamburg Eppendorf, Martini Klin Prostate Canc Ctr, 52 Martinistr, D-20246 Hamburg, Germany
[2] IRCCS Osped Policlin San Martino, Genoa, Italy
[3] Univ Hosp Hamburg Eppendorf, Dept Diagnost & Intervent Radiol & Nucl Med, Hamburg, Germany
[4] Univ Hosp Hamburg Eppendorf, Dept Surg, Hamburg, Germany
[5] Univ Hosp Hamburg Eppendorf, Dept Pathol, Hamburg, Germany
[6] Univ Hosp Hamburg Eppendorf, Dept Oncol, Hamburg, Germany
[7] Univ Hosp Hamburg Eppendorf, Dept Urol, Hamburg, Germany
来源：
CENTRAL EUROPEAN JOURNAL OF UROLOGY | 2023年 / 76卷 / 03期
关键词：
prostate cancer; prostate-specific membrane antigen; liver; radioguided surgery;
D O I：
10.5173/ceju.2023.69
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
We present the case of a patient who underwent an open radical prostatectomy with pelvic lymph node dissection (Gleason 4+3, pT3a pN1 R0) in March 2017. In November 2020, prostate-specific membrane antigen (PSMA) -radioguided salvage lymph node dissection was planned due to a single left para-rectal lymph node at a [68Ga] Ga-PSMA-I&T PET. In January 2022, the [68Ga] Ga-PSMA-I&T PET showed an isolated liver lesion. Biopsy confirmed prostate adenocarcinoma. A liver segmentectomy was performed. A complete biochemical response was reported until the last follow-up (December 2022). Prostate-specific membrane antigen positron emission tomography (PSMA PET)-directed metastasis-directed therapy may be an effective treatment in selected cases, allowing a benefit in the oncological outcome.
引用
收藏
页码：182 / 185
页数：4
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