COVID-19: a modern trigger for Guillain-Barre syndrome, myasthenia gravis, and small fiber neuropathy

被引:2
|
作者
Gomez, Francisco [1 ]
Mehra, Ashir [1 ]
Ensrud, Erik [1 ]
Diedrich, Daniel [2 ]
Laudanski, Krzysztof [2 ]
机构
[1] Univ Missouri, Dept Neurol, Columbia, MO 65211 USA
[2] Mayo Clin, Dept Anesthesiol & Perioperat Care, Rochester, MN USA
关键词
COVID-19; SARS-CoV-2; peripheral neuropathy; Guillain-Barre; GBS; myasthenia gravis; small fiber neuropathy; PLASMA-EXCHANGE; PATHOGENESIS; AUTOIMMUNE;
D O I
10.3389/fnins.2023.1198327
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
COVID-19 infection has had a profound impact on society. During the initial phase of the pandemic, there were several suggestions that COVID-19 may lead to acute and protracted neurologic sequelae. For example, peripheral neuropathies exhibited distinctive features as compared to those observed in critical care illness. The peripheral nervous system, lacking the protection afforded by the blood-brain barrier, has been a particular site of sequelae and complications subsequent to COVID-19 infection, including Guillain-Barre syndrome, myasthenia gravis, and small fiber neuropathy. We will discuss these disorders in terms of their clinical manifestations, diagnosis, and treatment as well as the pathophysiology in relation to COVID-19.
引用
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页数:13
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