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Diagnosis of COVID-19 associated arthritis in patients with or without underlying rheumatic and musculoskeletal disease supported by musculoskeletal ultrasound: a case series from three European centres
被引:5
|作者:
Vogler, D.
[1
]
Ruscitti, P.
[2
]
Navarini, L.
[3
]
Giacomelli, R.
[4
]
Iagnocco, A.
[5
]
Hoff, P.
[1
]
Burmester, G. -R.
[1
]
Ohrndorf, S.
[1
]
机构:
[1] Charite Univ Med Berlin, Dept Rheumatol & Clin Immunol, Berlin, Germany
[2] Univ Aquila, Dept Biotechnol & Appl Clin Sci, Laquila, Italy
[3] Fdn Policlin Univ Campus Biomed, Immunorheumatol Unit, Rome, Italy
[4] Univ Campus Biomedico Roma, Dept Med, Rheumatol Immunol & Clin Med Res Unit, Rome, Italy
[5] Univ Torino, Acad Rheumatol Ctr, Turin, Italy
关键词:
case series;
COVID-19;
reactive arthritis;
virus-related arthritis;
RMD;
flares;
musculoskeletal ultrasound;
INFECTION;
D O I:
10.55563/clinexprheumatol/an1yrh
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objective The coronavirus disease 19 (COVID-19) pandemic concerns the field of rheumatology in many ways. Arthritis in conjunction with COVID-19 is increasingly reported. However, clinical data are still limited and there is lack of a detailed characterisation of COVID-19 associated arthritis by musculoskeletal ultrasound (MSUS). This case series reports different forms of COVID-19 associated arthritis supported by MSUS in patients with or without underlying rheumatic and musculoskeletal disease (RMD). Methods From March 2020 to July 2021, adult patients (n=10) with arthritis timely related to COVID-19 were assessed in three European centres by clinical and laboratory values and additionally MSUS. Results In the group without underlying RMD (n=6), two patients presented with polyarticular arthralgia during severe COVID-19, swelling was rarely seen and MSUS demonstrated arthritis only in a few joints affected. The other four patients showed arthritis four to 16 weeks after mild or moderate COVID-19 (without hospitalisation): polyarthritis (n=1), oligoarthritis of the upper and lower limb (n=2), and in one case, late-onset rheumatoid arthritis (LORA) was newly diagnosed. In the group with an underlying RMD (n=4), an increase of disease activity was reported by MSUS during mild and mild-moderate COVID-19. In general, MSUS often presented power Doppler (PD) positive synovitis and tenosynovitis. Conclusion In our patients without underlying RMD, arthritides associated with COVID-19 are comparable to the clinical picture of a reactive arthritis (ReA) or other virus-related arthritides (e.g. parvovirus B19). New onset or flares of RMD possibly triggered by COVID-19 are noteworthy.
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页码:656 / 666
页数:11
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