Health-related quality of life among people who inject drugs in Australia

被引:4
|
作者
Cheng, Qinglu [1 ]
Bajis, Sahar [1 ]
Cunningham, Evan [1 ]
Shih, Sophy T. F. [1 ]
Schulz, Marcel [2 ,3 ]
Marshall, Alison D. [1 ,4 ]
Martin, Natasha K. [5 ]
Miners, Alec [6 ]
Hajarizadeh, Behzad [1 ]
Wiseman, Virginia [1 ,7 ]
Dore, Gregory J. [1 ]
Grebely, Jason [1 ]
机构
[1] UNSW Sydney, Kirby Inst, Wallace Wurth Bldg,High St, Sydney, NSW 2052, Australia
[2] UNSW Med, St Vincents Clin Sch, Sydney, NSW, Australia
[3] St Vincents Hosp, Dept Clin Pharmacol & Toxicol, Sydney, NSW, Australia
[4] UNSW Sydney, Ctr Social Res Hlth, Sydney, NSW, Australia
[5] Univ Calif San Diego, Div Infect Dis & Global Publ Hlth, La Jolla, CA USA
[6] London Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London, England
[7] London Sch Hyg & Trop Med, Dept Global Hlth & Dev, London, England
基金
英国医学研究理事会;
关键词
Health-related quality of life; EQ-5D-3L; People who inject drugs; Hepatitis C; Liver fibrosis; HEPATITIS-C VIRUS; AUDIT-C; FACILITY; USERS; EQ-5D;
D O I
10.1007/s11136-023-03465-3
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
PurposeThere is limited research on health-related quality of life (HRQoL) among people who inject drugs (PWID). We aimed to evaluate factors associated with HRQoL among a cohort of PWID in Australia.MethodsParticipants were enrolled in an observational cohort study (the LiveRLife Study) between 2014 and 2018 at 15 sites in Australia. They provided fingerstick whole-blood samples for point-of-care HCV RNA testing and underwent transient elastography to assess liver disease. Participants completed the EQ-5D-3L survey at enrolment. Regression models were used to assess the impact of clinical and socioeconomic characteristics on the EQ-5D-3L scores.ResultsAmong 751 participants (median age, 43 years; 67% male), 63% reported injection drug use in the past month, 43% had current HCV infection, and 68% had no/mild liver fibrosis (F0/F1). The mean EQ-5D-3L and EQ-VAS scores were 0.67 and 62, respectively, for the overall study population. There was no significant difference in the EQ-5D-3L scores among people with and without recent injecting drug use (mean: 0.66 vs. 0.68, median: 0.73 vs. 0.78, P = 0.405), and among people receiving and not receiving opioid agonist therapy (mean: 0.66 vs. 0.68, median: 0.73 vs. 0.76, P = 0.215). Participants who were employed were found to have the highest mean EQ-5D-3L (0.83) and EQ-VAS scores (77). The presence of current HCV infection, liver fibrosis stage, and high-risk alcohol consumption had little impact on HRQoL.ConclusionsThe study findings provide important HRQoL data for economic evaluations, useful for guiding the allocation of resources for HCV elimination strategies and interventions among PWID.
引用
收藏
页码:3195 / 3207
页数:13
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