Persulfate promoted carbamoylation of N-arylacrylamides and N-arylcinnamamides with 4-carbamoyl-Hantzsch esters

被引：3
|
作者：
Jing, Qi [1 ,2 ]
Qiao, Fu-Ci [1 ]
Sun, Jing [2 ]
Wang, Jing-Yun [1 ]
Zhou, Ming-Dong [1 ,2 ]
机构：
[1] Shenyang Univ Chem Technol, Coll Chem Engn, Shenyang 110142, Peoples R China
[2] Liaoning Petrochem Univ, Sch Petrochem Engn, Fushun 113001, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 37期
关键词：
ACTIVATED ALKENES; ALKYLATION REAGENTS; 4-ALKYL-1,4-DIHYDROPYRIDINES; HETEROCYCLES; CYCLIZATION; PROGRESS;
D O I：
10.1039/d3ob01240a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Carbamoyl-Hantzsch esters were used as carbamoyl radical precursors for oxidative carbamoylation of N-arylacrylamides and N-arylcinnamamides in the presence of inexpensive persulfates. This protocol can be applied to a broad range of substrates with various functional groups, providing a variety of 3,3-disubstituted oxindoles and 3,4-disubstituted dihydroquinolin-2(1H)-ones in moderate to good yields via an intermolecular addition/cyclization process.
引用
收藏
页码：7530 / 7534
页数：5
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